Ro52 antigen has recently been identified as TRIM21 protein, but the clinical significance of
anti-Ro52/TRIM21 antibodies remains controversial. The aim of this multicentric study was …

Paradoxically, reactive oxygen species (ROS) can promote normal cellular proliferation and
carcinogenesis, and can also induce apoptosis of tumor cells. In this report, we study the …

Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease
characterized by the involvement of multiple organs and an immune response against nuclear …

Systemic sclerosis (SSc) is a connective tissue disorder of great clinical heterogeneity. Its
pathophysiology remains unclear. Our aim was to evaluate the relative roles of reactive oxygen …

… After the provision of written informed consent from all patients, serum samples were
obtained at the time of study inclusion and stored at 80C. Serologic tests were performed in a …

Objectives: To investigate the role of reactive oxygen species (ROS) in the development of
the various patterns of systemic sclerosis (SSc) and the mechanisms of ROS production by …

… flushed with argon and incubated at 60C for 1 hour. After the … ), for 24 hours at 37C. The
reaction was terminated by boiling … carbonate for 16 hours at 37C. After PNGase F digestion, the …

Objective. Anticyclic citrullinated peptide antibodies (anti-CCP) are considered specific markers
of rheumatoid arthritis (RA) and have been included in the revised classification criteria …

… Laboratory tests included erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP),
as well as infliximab trough levels, which were measured in the morning prior to each …

… were then frozen at –20C within 2 h after centrifugation and stored at –30C within 12 h until
… A second tube, also stored at –30C, was thawed in 2007 and divided into five aliquots, three …