Functions of antimicrobial peptides in host defense and immunity
C Beisswenger, R Bals - Current Protein and Peptide Science, 2005 - ingentaconnect.com
… , a pro segment, and a C-terminal cationic peptide that has … the correct folding of the C-terminus,
intracellular trafficking, … AMPs are stored in cells as propeptides or mature C-terminal …
intracellular trafficking, … AMPs are stored in cells as propeptides or mature C-terminal …
[HTML][HTML] IL-17 cytokines and chronic lung diseases
… All IL-17 cytokines harbor five conserved cysteine residues at the C-terminus and assemble
into homodimers [2]. In addition, IL-17A can form a heterodimer together with IL-17F. By …
into homodimers [2]. In addition, IL-17A can form a heterodimer together with IL-17F. By …
Antimicrobial peptides in lung inflammation
C Beisswenger, R Bals - Mechanisms of Epithelial Defense, 2005 - karger.com
… cathepsin L inhibitor) but show substantial heterogeneity in the C-terminal domain … family
with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett 1995;374:…
with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett 1995;374:…
Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure
R Shaykhiev, C Beißwenger… - … of Physiology-Lung …, 2005 - journals.physiology.org
… Formation of lamellipodia (arrow, C) at the wound edge treated with 5 μg/ml LL-37 (A) or in
… C: LL-37 exposure did not induce apoptosis in an annexin binding assay in NCI-H292 cells …
… C: LL-37 exposure did not induce apoptosis in an annexin binding assay in NCI-H292 cells …
Suppression of pulmonary innate host defence in smokers
C Herr, C Beisswenger, C Hess, K Kandler, N Suttorp… - Thorax, 2009 - thorax.bmj.com
… 100 μl of samples were added into each well and incubated overnight at 4C. A series of
seven dilutions of recombinant hBD-215 was included as standard. Wells were washed and …
seven dilutions of recombinant hBD-215 was included as standard. Wells were washed and …
Microbial DNA induces a host defense reaction of human respiratory epithelial cells
J Platz, C Beisswenger, A Dalpke… - The Journal of …, 2004 - journals.aai.org
… C, hBD-2 mRNA induction following stimulation from the apical or the basolateral side. We
… 4 C). This effect was more pronounced after application to the apical side of the culture. …
… 4 C). This effect was more pronounced after application to the apical side of the culture. …
Allergic airway inflammation inhibits pulmonary antibacterial host defense
C Beisswenger, K Kandler, C Hess, H Garn… - The Journal of …, 2006 - journals.aai.org
… The BALF was centrifuged at 300 × g for 10 min at 4C to obtain alveolar cells and cell-free
lavage fluid. The cell-free lavage fluids were kept at −80C. Alveolar cells were suspended in 1 …
lavage fluid. The cell-free lavage fluids were kept at −80C. Alveolar cells were suspended in 1 …
IL-17C mediates the recruitment of tumor-associated neutrophils and lung tumor growth
…, T Spieker, R Wiewrodt, R Bals, C Beisswenger - Oncogene, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is associated with an increased risk for lung
cancer and an aberrant microbiota of the lung. Microbial colonization contributes to chronic …
cancer and an aberrant microbiota of the lung. Microbial colonization contributes to chronic …
[HTML][HTML] Vitamin D and its analogues decrease amyloid-β (Aβ) formation and increase Aβ-degradation
…, H Stötzel, K Endres, C Herr, C Beisswenger… - International journal of …, 2017 - mdpi.com
… Identical to the vitamin D 3 analogue maxacalcitol, paricalcitol contains a hydroxyl group
at C 1 and C 25 , but a vitamin D 2 instead of a vitamin D 3 side chain. 1-hydroxylated …
at C 1 and C 25 , but a vitamin D 2 instead of a vitamin D 3 side chain. 1-hydroxylated …
FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells
…, MD Menger, R Bals, C Beisswenger - The Journal of …, 2013 - journals.aai.org
… qRT-PCR was performed with a reaction mix including the SensiMix SYBR & Fluorescein
Kit (Bioline) using the iCycler (Bio-Rad) with a two-step protocol (15 s at 95C and 45 s at 60C). …
Kit (Bioline) using the iCycler (Bio-Rad) with a two-step protocol (15 s at 95C and 45 s at 60C). …