Background: The idea of self-management is to teach patients how to carry out the activities
of daily living optimally in the face of their physiological impairment, and to prevent or …

An imbalance between oxidative stress and antioxidative capacity is thought to play an
important role in the development and progression of chronic obstructive pulmonary disease (…

Background Increased oxidative stress is important in the pathogenesis of chronic
obstructive pulmonary disease (COPD). We postulated that treatment with the antioxidant N-…

… Klein JJ, van der Palen J, Uil SM, Zielhuis GA, Seydel ER, van Herwaarden CL. Benefit
from the inclusion of selftreatment guidelines to a self- management programme for adults with …

Corticosteroids may cause myopathy of both skeletal and respiratory muscles. This is of specific
clinical importance in patients with chronic obstructive pulmonary disease (COPD), who …

The aim of this double-blind single center study (the COPE study) was to investigate the
effect of discontinuation of the inhaled corticosteroid fluticasone propionate (FP) on …

This study investigated the influence of the use of different types of inhalers on the adequacy
of inhalation technique among adult asthmatics. Three hypotheses were tested: first, …

BACKGROUND It is important to diagnose asthma at an early stage as early treatment may
improve the prognosis in the long term. However, many patients do not present at an early …

In the present study, we hypothesized that exhaustive exercise in patients with chronic
obstructive pulmonary disease (COPD) results in glutathione oxidation and lipid peroxidation and …

The aim of this study was to assess the effects of a comprehensive self-management
intervention on health-related quality of life (HRQoL), symptoms and walking distance in patients …