Background Recurrent stroke is a frequent, disabling event after ischemic stroke. This study
compared the efficacy and safety of two antiplatelet regimens — aspirin plus extended-…

Background Prolonged lowering of blood pressure after a stroke reduces the risk of recurrent
stroke. In addition, inhibition of the renin–angiotensin system in high-risk patients reduces …

Intracellular recordings in vivo from noradrenergic neurons of the rat locus coeruleus showed
that membrane potential was hyperpolarized by the administration of clonidine (an α 2 -…

… C 1 and C 2 are from the same neuron recorded at different oscilloscope sweep speeds,
as is the case for F 1 and F 2. Notice the continuum of waveform variations for presumed …

Background The treatment of ischaemic stroke with neuroprotective drugs has been unsuccessful,
and whether these compounds can be used to reduce disability after recurrent stroke …

… Clinical trials have demonstrated that buspirone (BuSpar c~) is effective in the treatment of
anxiety with efficacy and dosage comparable to diazepam or chlorazepate. Buspirone has a …

… and freeze-dried in a vacuum at 25C for 3 to 4 days. The dried tissue then was exposed for
1.5 hr to formaldehyde gas generated at 80C from paraformaldehyde powder (1 gm/lOO ml of …

… Animals were anesthetized with chloral hydrate (400 mg/kg, ip) and mounted in a stereotaxic
frame; body temperature was maintained at 35-37 C. A midline burr hole was drilled in the …

… Oxygenated ACSF at 36.5 ___ 0.5C continuously flowed over the stage. A thorough perfusion
of both sides of the slice was insured by covering the slice with a single layer of surgical …

… The samples were stored at -75C for up to 2 weeks prior to analysis. Other groups of rats
were decapitated and the skulls dipped into liquid nitrogen. The brains were then dissected, in …