Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized …

…, MI Restrepo, A Anzueto, MS Niederman, C Agustí - Jama, 2015 - jamanetwork.com
… trial conducted in 3 Spanish teaching hospitals involving patients with both severe
community-acquired pneumonia and a high inflammatory response, which was defined as a level of …

Bacterial colonisation in patients with bronchiectasis: microbiological pattern and risk factors

J Angrill, C Agusti, R De Celis, A Rańó, J Gonzalez… - Thorax, 2002 - thorax.bmj.com
Background: A study was undertaken to investigate the incidence, diagnostic yield of non-invasive
and bronchoscopic techniques, and risk factors of airway colonisation in patients with …

Bacterial colonization of distal airways in healthy subjects and chronic lung disease: a bronchoscopic study

…, A Xaubet, J Gonzalez, C Agusti… - European …, 1997 - Eur Respiratory Soc
In contrast to the healthy population, distal airway bacterial colonization may occur in patients
with chronic lung diseases, who often have altered pulmonary defences. However, the …

Efficacy predictors of lung volume reduction with Zephyr valves in a European cohort

…, JJ Egan, S Gasparini, C Agusti… - European …, 2012 - Eur Respiratory Soc
The Endobronchial Valve for Emphysema Palliation Trial (VENT) was a multi-centre,
prospective, randomised, controlled trial conducted to evaluate the safety and effectiveness of …

Bronchial inflammation and colonization in patients with clinically stable bronchiectasis

J Angrill, C Agusti, R DE CELIS, X Filella… - American journal of …, 2001 - atsjournals.org
To evaluate the bronchial inflammatory response and its relationship to bacterial colonization
in bronchiectasis, we performed a bronchoalveolar lavage (BAL) in 49 patients in stable …

Pulmonary infiltrates in non-HIV immunocompromised patients: a diagnostic approach using non-invasive and bronchoscopic procedures

…, C Agusti, P Jimenez, J Angrill, N Benito, C Danes… - Thorax, 2001 - thorax.bmj.com
BACKGROUND The development of pulmonary infiltrates is a frequent life threatening
complication in immunocompromised patients, requiring early diagnosis and specific treatment. In …

Corticosteroids in severe pneumonia

O Sibila, C Agusti, A Torres - European Respiratory Journal, 2008 - Eur Respiratory Soc
The mortality rate in severe community- or hospital-acquired pneumonia is very high, ranging
20–50%. Despite advances in antimicrobial therapy and supportive measures, this rate …

Animal models of ventilator-associated pneumonia

CM Luna, O Sibila, C Agusti… - European Respiratory …, 2009 - Eur Respiratory Soc
Animal models are an essential step between “in vitro” testing and clinical studies. Different
animal models have been useful for the study of pathophysiology, diagnosis and therapy in …

Bronchoscopic validation of the significance of sputum purulence in severe exacerbations of chronic obstructive pulmonary disease

N Soler, C Agusti, J Angrill, JP De la Bellacasa… - Thorax, 2007 - thorax.bmj.com
Background: Antibiotics are commonly prescribed in exacerbations of chronic obstructive
pulmonary disease (COPD). However, the role of bacteria in these exacerbations is …

Pulmonary function tests and CT scan in the management of idiopathic pulmonary fibrosis

…, C Agustí, P Luburich, J Roca, C Monton… - American journal of …, 1998 - atsjournals.org
Relationships between pulmonary function testing and high-resolution computed tomography
(HRCT) were studied in 39 untreated patients with idiopathic pulmonary fibrosis (IPF) at …