Association of EGFR L858R mutation in circulating free DNA with survival in the EURTAC trial

…, C Queralt, I de Aguirre, B Melloni… - JAMA …, 2015 - jamanetwork.com
Importance The EURTAC trial demonstrated the greater efficacy of erlotinib compared with
chemotherapy for the first-line treatment of European patients with advanced non–small-cell …

Multimodal nutritional rehabilitation improves clinical outcomes of malnourished patients with chronic respiratory failure: a randomised controlled trial

…, F Costes, B Wuyam, T Similowski, B Melloni… - Thorax, 2011 - thorax.bmj.com
Boris Melloni23, … Court-Fortune, F Costes, B Januel, M Charles); (4) Limoges, France: CHU
du Cluzeau-Dupuytren (B Melloni, MT Antonini, JC Desport, JM Ribardière, F Dalmay), ALAIR…

Sortilin mediates the release and transfer of exosomes in concert with two tyrosine kinase receptors

CM Wilson, T Naves, F Vincent, B Melloni… - Journal of cell …, 2014 - journals.biologists.com
The transfer of exosomes containing both genetic and protein materials is necessary for the
control of the cancer cell microenvironment to promote tumor angiogenesis. The nature and …

Treatable traits in the NOVELTY study

…, P Mabire, G Mahay, S Martinez, B Melloni… - …, 2022 - Wiley Online Library
Background and objective Asthma and chronic obstructive pulmonary disease (COPD) are
two prevalent and complex diseases that require personalized management. Although a …

[HTML][HTML] Sortilin limits EGFR signaling by promoting its internalization in lung cancer

…, A Magnaudeix, K Durand, F Bertin, B Melloni… - Nature …, 2017 - nature.com
Tyrosine kinase receptors such as the epidermal growth factor receptor (EGFR) transduce
information from the microenvironment into the cell and activate homeostatic signaling …

[HTML][HTML] Frequent productive cough: symptom burden and future exacerbation risk among patients with asthma and/or COPD in the NOVELTY study

…, P Mabire, G Mahay, S Martinez, B Melloni… - Respiratory …, 2022 - Elsevier
Introduction Persistent cough with sputum production is an important clinical trait in chronic
obstructive pulmonary disease (COPD). We defined “frequent productive cough” based on 2 …

[HTML][HTML] Severe asthma standard-of-care background medication reduction with benralizumab: ANDHI in practice substudy

…, Y Douadi, G Mahay, G Devouassoux, B Melloni… - The Journal of Allergy …, 2023 - Elsevier
Background The phase IIIb, randomized, parallel-group, placebo-controlled ANDHI double-blind
(DB) study extended understanding of the efficacy of benralizumab for patients with …

[HTML][HTML] Therapy response evaluation with FDG-PET/CT in small cell lung cancer: a prognostic and comparison study of the PERCIST and EORTC criteria

…, A El Badaoui, A Hitzel, JB Woillard, B Melloni… - Cancer …, 2013 - ncbi.nlm.nih.gov
Introduction: Small cell lung cancer (SCLC) is an aggressive form of lung cancer with poor
prognosis. Adequate staging and therapeutic evaluation is necessary for therapy planning. …

[HTML][HTML] Neutrophil-to-lymphocyte ratio evolution is an independent predictor of early progression of second-line nivolumab-treated patients with advanced non-small …

…, N Delacourt, J Ballouhey, T Egenod, B Melloni… - PloS one, 2019 - journals.plos.org
Introduction Although second-line immunotherapy obtained better outcomes than chemotherapy
for patients with advanced non-small–cell lung cancers (NSCLCs), it is expensive and …

[HTML][HTML] The burden of mild asthma: Clinical burden and healthcare resource utilisation in the NOVELTY study

…, G Mahay, Y Ide, S Martinez, M Inomata, B Melloni… - Respiratory …, 2022 - Elsevier
Background Patients with mild asthma represent a substantial proportion of the population
with asthma, yet there are limited data on their true burden of disease. We aimed to describe …