Complex chronic comorbidities of COPD

LM Fabbri, F Luppi, B Beghé… - European Respiratory …, 2008 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is defined by fixed airflow limitation
associated with an abnormal pulmonary and systemic inflammatory response of the lungs to …

[HTML][HTML] Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis

…, V Maravić-Stojković, A Verduri, B Beghé… - The Lancet infectious …, 2018 - thelancet.com
Background In February, 2017, the US Food and Drug Administration approved the blood
infection marker procalcitonin for guiding antibiotic therapy in patients with acute respiratory …

MACVIA‐ARIA Sentinel NetworK for allergic rhinitis (MASK‐rhinitis): the new generation guideline implementation

…, AK Baigenzhin, C Barbara, ED Bateman, B Beghé… - Allergy, 2015 - Wiley Online Library
Several unmet needs have been identified in allergic rhinitis: identification of the time of
onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, …

Airway inflammation in severe chronic obstructive pulmonary disease: relationship with lung function and radiologic emphysema

…, M Miniati, S Baraldo, F Rea, B Beghé… - American journal of …, 2002 - atsjournals.org
The lung pathology of severe chronic obstructive pulmonary disease (COPD) has been
poorly investigated. We examined surgical specimens obtained from patients with severe (forced …

Chronic obstructive pulmonary disease exacerbation fundamentals: Diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma …

…, C Taube, T Welte, A de Roux, B Beghé… - The lancet respiratory …, 2021 - thelancet.com
Background ANDHI was done to assess the efficacy of benralizumab, including onset of effect
and impact on health-related quality of life (HRQOL), exacerbation rate, lung function, and …

Is diet partly responsible for differences in COVID‐19 death rates between and within countries?

…, M Bedolla Barajas, B Beghé… - Clinical and …, 2020 - Wiley Online Library
Reported COVID‐19 deaths in Germany are relatively low as compared to many European
countries. Among the several explanations proposed, an early and large testing of the …

Airway inflammation in childhood asthma

…, F Calabrese, M Tura, R Zuin, B Beghé… - American journal of …, 2003 - atsjournals.org
Airway pathology has been extensively investigated in adulthood asthma, whereas only few
studies examined bronchial biopsies in childhood asthma. To evaluate the airway pathology …

Polymorphisms in the interleukin‐4 and interleukin‐4 receptor α chain genes confer susceptibility to asthma and atopy in a Caucasian population

B Beghé, S Barton, S Rorke, Q Peng… - Clinical & …, 2003 - Wiley Online Library
Background IL‐4 by binding to its receptor (IL‐4R) is essential for the development of
airway inflammation present in asthma, through the induction of IgE synthesis in B cells and …

Neutrophilic infiltration within the airway smooth muscle in patients with COPD

S Baraldo, G Turato, C Badin, E Bazzan, B Beghe… - Thorax, 2004 - thorax.bmj.com
Background: COPD is an inflammatory disorder characterised by chronic airflow limitation,
but the extent to which airway inflammation is related to functional abnormalities is still …