BACKGROUND: Asthma is characterized by increased airway narrowing in response to
nonspecific stimuli. The disorder is influenced by both environmental and genetic factors. …

Artificial nanoparticles accumulate a protein corona layer in biological fluids, which significantly
influences their bioactivity. As nanosized obligate intracellular parasites, viruses share …

Cadmium in tobacco smoke may contribute to the development of pulmonary emphysema.
However, there is poor understanding of the mechanisms behind the pathogenic role of …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and a leading
cause of mortality and morbidity worldwide. The aim of this study was to investigate the sex …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality; however,
the role of inflammatory mediators in its pathobiology remains unclear. The aim of this study …

Rationale: The role of the presumed Th17 cytokine IL-26 in antibacterial host defense of the
lungs is not known. Objectives: To characterize the role of IL-26 in antibacterial host defense …

Background Asthma is a chronic inflammatory lung disease that causes significant morbidity
and mortality worldwide. Air pollutants such as particulate matter (PM) and oxidants are …

In this pilot study, we examined associations between local interleukin (IL)-26, disease
severity and biomarkers of Th2-mediated inflammation in a well-defined cohort of pediatric …

Interleukin (IL)-26 is abundant in human airways and this cytokine is involved in the local
immune response to a bacterial stimulus in vivo. Specifically, local exposure to the toll-like …

Long-term tobacco smokers with chronic obstructive pulmonary disease (COPD) or chronic
bronchitis display an excessive accumulation of neutrophils in the airways; an inflammation …