Effect of lipoteichoic acid on IL-2 and IL-5 release from T lymphocytes in asthma and COPD

Z Mat, B Grensemann, Y Yakin, J Knobloch… - International …, 2012 - Elsevier
Susceptibility to infections with gram-positive bacteria, which are an important trigger of
exacerbations, is increased in COPD and asthma. Unraveling the underlying mechanisms may …

Simvastatin requires activation in accessory cells to modulate T-cell responses in asthma and COPD

J Knobloch, Y Yakin, S Körber, B Grensemann… - European Journal of …, 2016 - Elsevier
T-cell-dependent airway and systemic inflammation triggers the progression of chronic
obstructive pulmonary disease (COPD) and asthma. Retrospective studies suggest that …

Simvastatin suppresses the activity of Th2 and Tc2 cells in atopic asthma and in COPD

J Knobloch, Y Yakin, B Grensemann… - European …, 2014 - Eur Respiratory Soc
Rationale: Retrospective studies suggest simvastatin (SA) as an alternative anti-inflammatory
therapy for asthma and COPD. It is unknown, which cell types are influenced by SA. SA …

The T-helper cell type 1 immune response to gram-negative bacterial infections is impaired in COPD

J Knobloch, K Schild, D Jungck, K Urban… - American journal of …, 2011 - atsjournals.org
Rationale: The increased susceptibility to bacterial infections in chronic obstructive pulmonary
disease (COPD) is critical for exacerbations. Toll-like receptor-4 (TLR4) detects bacteria …

Causes of Disease in the Hippocratic Corpus

JC Kosak - Heroic Measures, 2004 - brill.com
… 9 These two conceptions of epidemic disease causation have interesting social consequences,
according to Barbara Leavy. In her book, To Blight with Plague: Studies in a Literary …

THE EIGHT MONTHS'CHILD AND THE ETIQUETTE OF BIRTH:" OBSIT OMEN!"

AE Hanson - Bulletin of the History of Medicine, 1987 - JSTOR
… 20 Eg, Grensemann argues that belief in the inevitable death of the eight months' child
belongs to the Coan School in "Der Arzt Polybos als Verfasser hippokratischen Schriften," …

A systemic defect in Toll-like receptor 4 signaling increases lipopolysaccharide-induced suppression of IL-2-dependent T-cell proliferation in COPD

J Knobloch, SJ Chikosi, S Yanik… - … of Physiology-Lung …, 2016 - journals.physiology.org
The susceptibility to bacterial infections is increased in chronic obstructive pulmonary disease
(COPD). This promotes exacerbations. IL-2 triggers CD4 + /Th1-cell proliferation, which is …

Articles in PresS. Am J Physiol Lung Cell Mol Physiol (October 23, 2015). doi: 10.1152/ajplung. 00367.2014

J Knobloch, SJ Chikosi, S Yanik… - Am J Physiol Lung …, 2015 - journals.physiology.org
The susceptibility to bacterial infections is increased in COPD. This promotes exacerbations.
IL-2 27 triggers CD4+/Th1-cell proliferation, which is important for infection defense. …

The symptom and the subject: the emergence of the physical body in ancient Greece

B Holmes - 2010 - torrossa.com
Nothing drives us to ask why like the austere truth of human suffering. Hesiod, the first
didactic poet in the Greek literary tradition, takes up the question on a grand scale early in the …

Hippocratic recipes: oral and written transmission of pharmacological knowledge in fifth-and fourth-century Greece

L Totelin - Hippocratic Recipes, 2008 - brill.com
Grensemann did not pronounce himself on the origin of A1, but maintained that A2 was
produced in Cnidus and contained material by Euryphon and perhaps Herodicus. By 1987, the …