[HTML][HTML] Inflammatory cytokines in pulmonary hypertension

A Groth, B Vrugt, M Brock, R Speich, S Ulrich… - Respiratory …, 2014 - Springer
… These stimulated B cells produce autoantibodies … , B cells in peripheral blood from idiopathic
PAH patients show a different RNA expression profile suggesting that in PAH patients B

The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma

…, I Kimber, RJ Dearman, B Vrugt… - Clinical & …, 2003 - Wiley Online Library
Background The extent of epithelial injury in asthma is reflected by expression of the epidermal
growth factor receptor (EGFR), which is increased in proportion to disease severity and is …

[HTML][HTML] Heterogeneity in malignant pleural mesothelioma

K Oehl, B Vrugt, I Opitz, M Meerang - International journal of molecular …, 2018 - mdpi.com
Despite advances in malignant pleural mesothelioma therapy, life expectancy of affected
patients remains short. The limited efficiency of treatment options is mainly caused by inter- and …

Bronchial angiogenesis in severe glucocorticoid-dependent asthma

B Vrugt, S Wilson, A Bron, ST Holgate… - European …, 2000 - Eur Respiratory Soc
… All sections for each antibody were examined simultaneously by a blinded investigator (B.
Vrugt). Only positively stained vessels and nucleated, positively stained cells were counted at …

[HTML][HTML] Liver allograft failure after nivolumab treatment—a case report with systematic literature research

…, B Vrugt, M Nägeli, J Mangana, B Müllhaupt… - Transplantation …, 2018 - journals.lww.com
B, CT scan 9 months later with stable lymph node before nivolumab treatment 35 months
after liver transplantation. C, CT scan at the day of death 25 days after nivolumab treatment …

Increased Expression of p21waf Cyclin-Dependent Kinase Inhibitor in Asthmatic Bronchial Epithelium

…, JL Lordan, PH Howarth, B Vrugt… - American journal of …, 2003 - atsjournals.org
Because the asthmatic bronchial epithelium is characterized by widespread damage, we
postulated that this is associated with expression of cell cycle inhibitors that control proliferation…

Small cell carcinoma of the lung and large cell neuroendocrine carcinoma interobserver variability

…, RJ Van Suylen, W Timens, B Vrugt… - …, 2010 - Wiley Online Library
den Bakker MA, Willemsen S, Grünberg K, Noorduijn LA, van Oosterhout MFM, van Suylen
RJ, Timens W, Vrugt B, Wiersma‐van Tilburg A & Thunnissen FBJM (2010) Histopathology56…

[HTML][HTML] GAS5 long non-coding RNA in malignant pleural mesothelioma

…, J Kresoja-Rakic, N Echeverry, G Ziltener, B Vrugt… - Molecular cancer, 2014 - Springer
… GAS5 lncRNA silencing increases the expression of glucocorticoid responsive genes GILZ
(B) and SGK1 (C). Values are normalized with histones and shown as mean ± SD from three …

[HTML][HTML] Nuclear grade and necrosis predict prognosis in malignant epithelioid pleural mesothelioma: a multi-institutional study

…, M Sheaff, WD Travis, WT Vigneswaran, B Vrugt… - Modern Pathology, 2018 - Elsevier
… (b) Moderate nuclear atypia with mild variation is size and shape and conspicuous nucleoli.
… (b) Patients with a nuclear score of 1 had the best overall survival followed by scores of 2 …

[HTML][HTML] How asbestos drives the tissue towards tumors: YAP activation, macrophage and mesothelial precursor recruitment, RNA editing, and somatic mutations

…, C Aquino, B Vrugt, M de Perrot, B Schwaller… - Oncogene, 2018 - nature.com
… A significant decrease in the total number of T and B cells was observed in the peritoneal
lavage 12 … No difference for B cells was observed in the spleen. N = 6–8 mice. Mean ± SE. *…