Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease of unknown etiology;
however, apoptosis of lung alveolar epithelial cells plays a role in disease progression. This …

Idiopathic pulmonary fibrosis is an incurable disease of unknown etiology. Acute exacerbation
of idiopathic pulmonary fibrosis is associated with high mortality. Excessive apoptosis of …

Idiopathic pulmonary fibrosis is a progressive and fatal disease with a poor prognosis. Matrix
metalloproteinase-2 is involved in the pathogenesis of organ fibrosis. The role of matrix …

Acute lung injury (ALI) is a clinical syndrome characterized by a diffuse lung inflammation
that commonly evolves into acute respiratory distress syndrome and respiratory failure. The …

Background Coagulopathy is a major cause of morbidity and mortality in COVID-19 patients.
Hypercoagulability in COVID-19 results in deep vein thrombosis, thromboembolic …

Simple Summary Therapeutic efficacy of chemotherapy combined with immune checkpoint
inhibitors as first-line therapy has been previously demonstrated in extensive-stage small cell …

We examined the effects of 1, 3-dipropyl-8-cyclopentylxanthine(DPCPX) and (R)-7, 8-dihydro-8-ethyl-2-(3-noradamantyl)-4-propyl-lH-imidazo
[2, l-ilpurin-5 (4H)-one (KF20274), …

Background Immune checkpoint inhibitors have recently become the standard of care in the
first‐line treatment of extensive‐stage small cell lung cancer. Although immune‐related …

KW-5092 ({1-[2-[[[5-(piperidinomethyl)-2-furanyl] methyl] amino] ethyl]-2-imidazolidinylidene}
propanedinitrile fumarate) is a novel gastroprokinetic agent with acetylcholinesterase (…

The effects of adenosine and its related compounds on the cholinergic twitch response were
examined in electrically stimulated guinea pig ileum. Adenosine (3 x 10-'-10-5 M) and an …