Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis

A Kerrin, P Fitch, C Errington, D Kerr, L Waxman… - Thorax, 2017 - thorax.bmj.com
Rationale The pathogenesis of respiratory syncytial virus (RSV) bronchiolitis in infants
remains poorly understood. Mouse models implicate pulmonary T cells in the development of …

Identification of capsaicin-sensitive rectal mechanoreceptors activated by rectal distension in mice

NJ Spencer, A Kerrin, CA Singer, GW Hennig… - Neuroscience, 2008 - Elsevier
Rodents detect visceral pain in response to noxious levels of rectal distension. However,
the mechanoreceptors that innervate the rectum and respond to noxious levels of rectal …

Identification of functional intramuscular rectal mechanoreceptors in aganglionic rectal smooth muscle from piebald lethal mice

NJ Spencer, A Kerrin… - American Journal …, 2008 - journals.physiology.org
The mechanosensitive endings of low-threshold, slowly adapting pelvic afferents that
innervate the rectum have been previously identified as rectal intraganglionic laminar endings (…

Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury

A Kerrin, S Weldon, AHK Chung, T Craig, AJ Simpson… - Thorax, 2013 - thorax.bmj.com
Rationale We hypothesise that elafin levels in acute lung injury (ALI) decrease over time due,
in part, to proteolytic degradation as observed in other lung diseases. Objectives The aim …

B32 VIRAL INFECTION OF THE AIRWAY: Activated Conventional Lung Dendritic Cells In Infants With Severe Rsv Bronchiolitis

JK Schwarze, A Kerrin, P Fitch, D Kerr… - American Journal of …, 2014 - search.proquest.com
Methods: Infants intubated and ventilated due to severe RSV-bronchiolitis (n= 24) or for
planned surgery (controls with healthy lungs and without respiratory viral infection, n= 14) …

Decreased Levels In Elafin Due To Proteolytic Cleavage May Contribute To Alveolar Inflammation In The Pulmonary Compartment In Patients With Acute Lung Injury

A Kerrin, C O'Kane, M Shyamsundar… - … OF ACUTE LUNG …, 2011 - atsjournals.org
Introduction: is a potent serine protease inhibitor produced locally in the lung by epithelial
and inflammatory cells with anti-inflammatory properties. To assess the temporal changes in …

Decreased levels of elafin in the lungs of patients with acute lung injury as a result of proteolytic cleavage by the proteasome

C Taggart, A Kerrin, C O'Kane, S Weldon, A Chang… - 2012 - Eur Respiratory Soc
Unregulated protease activity may drive dysregulated pulmonary inflammation implicated in
acute lung injury (ALI). Elafin is a potent serine protease inhibitor produced locally in the …

[PDF][PDF] Identification of functional intramuscular rectal

SJB Muto, O McDonnell - Am J Physiol Gastrointest Liver Physiol, 2008 - academia.edu
Physiol 294: G855–G867, 2008. First published January 24, 2008; doi: 10.1152/ajpgi.
00502.2007.—The mechanosensitive endings of low-threshold, slowly adapting pelvic afferents …

[CITATION][C] Online Data Supplement

A Kerrin, S Weldon, AHK Chung, T Craig, AJ Simpson…

[CITATION][C] Professor Jürgen Schwarze

P Fitch, A Kerrin, A McFarlane, C Wilson, H Mcsorley