Introduction. Pulmonary arterial hypertension (PAH) is a rare disease that must be managed
in specialized centers; therefore, the availability of epidemiological national data is critical. …

The prevalence of high blood pressure (BP) at pediatric age has increased progressively,
one of the causes of which is obesity. However, the dominant etiology in this age group is …

Motivation Coiled coils are widespread protein domains involved in diverse processes
ranging from providing structural rigidity to the transduction of conformational changes. They …

Background Bosentan is recommended for symptomatic patients with Eisenmenger
syndrome due to simple congenital lesions such as atrial and ventricular septal defects (VSD). …

Congenital anomalies of the thoracic veins are rare yet important developmental abnormalities,
usually classified into systemic and pulmonary. They may be encountered incidentally; …

Canonical π-helices are short, relatively unstable secondary structure elements found in
proteins. They comprise seven or more residues and are present in 15% of all known protein …

Here a differential geometry (DG) representation of protein backbone is explored on the
analyses of protein conformational ensembles. The protein backbone is described by curvature, …

A Hipertensão Pulmonar (HP) era, até há bem pouco tempo, uma entidade obscura,
frequentemente não identificada, porque omissa nos processos comuns de diagnóstico e não …

Reports of Schistosoma mansoni strains resistant to praziquantel, the only therapeutic strategy
available for the treatment of schistosomiasis, have motivated the scientific community …

… da Silva AM 4 , … Reis A, Rocha N, Barros R, Martins A, Oliveira F, Diogo AN, da Silva AM,
Alvares S, Shiang T, Castro G, Agapito A, Pulmonary Vascular Disease Study Group of the …