Increased duration of mechanical ventilation is associated with decreased diaphragmatic force

G Hermans, A Agten, D Testelmans, M Decramer… - Critical Care, 2010 - Springer
Methods Prospective observational study in a medical ICU of a university hospital. TwPdi
BAMPS was measured in critically ill and mechanically ventilated patients. Briefly, the phrenic …

Unilateral changes of the multifidus in persons with lumbar disc herniation: a systematic review and meta-analysis

S Stevens, A Agten, A Timmermans, F Vandenabeele - The Spine Journal, 2020 - Elsevier
BACKGROUND Lumbar disc herniation (LDH) is one of the most often diagnosed degenerative
pathologies within the lumbar spine. Paraspinal muscle involvement could be a possible …

Atrophy and hypertrophy signalling in the diaphragm of patients with COPD

D Testelmans, T Crul, K Maes, A Agten… - European …, 2010 - Eur Respiratory Soc
We investigated whether atrophy and hypertrophy signalling were altered in the diaphragm
of chronic obstructive pulmonary disease (COPD) patients. We studied diaphragm fibre …

[PDF][PDF] Exercise intensity matters in chronic nonspecific low back pain rehabilitation

J Verbrugghe, A Agten, S Stevens… - Medicine & Science …, 2019 - paulogentil.com
No. 12, pp. 2434–2442, 2019. Introduction: Exercise therapy (ET) is advocated as a treatment
for chronic nonspecific low back pain (CNSLBP). However, therapy effect sizes remain low…

N-Acetylcysteine protects the rat diaphragm from the decreased contractility associated with controlled mechanical ventilation

A Agten, K Maes, A Smuder, SK Powers… - Critical care …, 2011 - journals.lww.com
Objective: Controlled mechanical ventilation results in diaphragmatic dysfunction, and
oxidative stress has been shown to be an important contributor to ventilator-induced diaphragm …

[HTML][HTML] High intensity training to treat chronic nonspecific low back pain: Effectiveness of various exercise modes

J Verbrugghe, A Agten, S Stevens, D Hansen… - Journal of Clinical …, 2020 - mdpi.com
High-intensity training (HIT) improves rehabilitation outcomes such as functional disability
and physical performance in several chronic disorders. Promising results were also found in …

[HTML][HTML] Fine-needle percutaneous muscle microbiopsy technique as a feasible tool to address histological analysis in young children with cerebral palsy and age …

…, AV Campenhout, ED Wachter, K Desloovere, A Agten… - Plos one, 2023 - journals.plos.org
Cerebral palsy (CP) is a heterogeneous group of motor disorders attributed to a non-progressive
lesion in the developing brain. Knowledge on skeletal muscle properties is important to …

High intensity training improves symptoms of central sensitization at six-month follow-up in persons with chronic nonspecific low back pain: Secondary analysis of a …

J Verbrugghe, A Agten, S Stevens… - Brazilian Journal of …, 2023 - Elsevier
Background High intensity training (HIT) improves disability and physical fitness in persons
with chronic nonspecific low back pain (CNSLBP). However, it remains unclear if HIT affects …

Biopsy samples from the erector spinae of persons with nonspecific chronic low back pain display a decrease in glycolytic muscle fibers

A Agten, S Stevens, J Verbrugghe, A Timmermans… - The Spine Journal, 2020 - Elsevier
BACKGROUND CONTEXT Low back pain (LBP) in Western Europe was classified as having
the highest disability and overall burden among 291 studied conditions. For an extensive …

Bortezomib partially protects the rat diaphragm from ventilator-induced diaphragm dysfunction

A Agten, K Maes, D Thomas, N Cielen… - Critical care …, 2012 - journals.lww.com
Objective: Controlled mechanical ventilation leads to diaphragmatic contractile dysfunction
and atrophy. Since proteolysis is enhanced in the diaphragm during controlled mechanical …