The natural history of childhood intra-thoracic tuberculosis: a critical review of literature from the pre-chemotherapy era [State of the Art]

…, RP Gie, HS Schaaf, AC Hesseling… - … of Tuberculosis and …, 2004 - ingentaconnect.com
The pre-chemotherapy literature documented the natural history of tuberculosis in childhood.
These disease descriptions remain invaluable for guiding public health policy and research…

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

…, GJ Churchyard, D Menzies, AC Hesseling… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis
remains out of control in several parts of the world including Africa and Asia. Although …

A refined symptom-based approach to diagnose pulmonary tuberculosis in children

…, RP Gie, AC Hesseling, HS Schaaf, C Lombard… - …, 2006 - publications.aap.org
BACKGROUND. Tuberculosis control programs place an almost exclusive emphasis on
adults with sputum smear-positive tuberculosis, because they are most infectious. However, …

Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an …

…, M Hatherill, AC Hesseling… - Journal of Infectious …, 2012 - academic.oup.com
There is a critical need for improved diagnosis of tuberculosis in children, particularly in
young children with intrathoracic disease as this represents the most common type of …

[HTML][HTML] Shorter treatment for nonsevere tuberculosis in African and Indian children

…, SB Welch, SM Graham, AC Hesseling… - … England Journal of …, 2022 - Mass Medical Soc
Background Two thirds of children with tuberculosis have nonsevere disease, which may be
treatable with a shorter regimen than the current 6-month regimen. Methods We conducted …

The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis

…, D Hannoun, M Hatherill, AM Hauri, AC Hesseling… - The Lancet, 2020 - thelancet.com
Background Tens of millions of children are exposed to Mycobacterium tuberculosis
globally every year; however, there are no contemporary estimates of the risk of developing …

The clinical epidemiology of childhood pulmonary tuberculosis: a critical review of literature from the pre-chemotherapy era [State of the Art]

…, RP Gie, HS Schaaf, AC Hesseling… - … of Tuberculosis and …, 2004 - ingentaconnect.com
The pre-chemotherapy literature represents an impressive body of evidence that clarifies
important epidemiological concepts in childhood tuberculosis. Reports describe the major …

The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children

AC Hesseling, BJ Marais, RP Gie, HS Schaaf… - Vaccine, 2007 - Elsevier
OBJECTIVES: Bacille Calmette-Guerin (BCG), a live attenuated Mycobacterium bovis vaccine,
poses a risk to human immunodeficiency virus (HIV)-infected children; this risk has not …

Clinical case definitions for classification of intrathoracic tuberculosis in children: an update

…, D Gnanashanmugam, AC Hesseling… - Clinical Infectious …, 2015 - academic.oup.com
Consensus case definitions for childhood tuberculosis have been proposed by an international
expert panel, aiming to standardize the reporting of cases in research focusing on the …

[HTML][HTML] Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data …

…, EM Netto, AC Lemos, AC Hesseling… - The Lancet Global …, 2022 - thelancet.com
Background BCG vaccines are given to more than 100 million children every year, but there
is considerable debate regarding the effectiveness of BCG vaccination in preventing …