Idiopathic pulmonary fibrosis (IPF) is a severe interstitial lung disease unresponsive to
currently available therapies. In IPF, initial alveolar epithelial cell damage leads to activation of …

There is a pressing need in antibiotic drug discovery for new drugs to counterbalance the
effects of multidrug resistance. Plants represent a viable platform for such endeavors owing to …

In an in vitro cytopathic effect inhibition assay with the H3N2 influenza virus A/Hong Kong/68
(HK/68), the bark extract of Burkea africana was found to be a promising antiviral lead with …

Four chalcones, (E)-3-(3-hydroxyphenyl)-1-phenylprop-2-en-1-one (A), (E)-3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one
(B), (E)-3-(4-hydroxyphenyl)-1-(4-methoxyphenyl)prop‑2-en-1-…

A series of readily synthesized and inexpensive aminoalkylated chalcones and diarylpropane
analogues (1–55) were synthesized and tested against chloroquinone-sensitive (D10 and …

Globalization and multidrug resistance are amongst the factors implicated in the resurgence
of infectious diseases in recent years. This has fostered a compelling need in drug …

Mental illnesses (MIs) such as anxiety, epilepsy, major depression, schizophrenia, sleep
disorder, and pain influence the quality of life severely. According to the World Health …

The aim of this study was to identify bioactive secondary metabolites from Ochna rhizomatosa
with potential inhibitory effects against HIV and Plasmodium falciparum. A phytochemical …

Wattle (Acacia mearnsii De Wild., Leguminosae) bark extract is used commercially to tan
leather and manufacture adhesives. The extract is treated with sodium hydrogen sulfite (sulfited…

The goal of this work is to use a variety of in-silico techniques to identify anti-diabetic agents
against DPP-IV enzyme from five main curcumin analogues. To produce the successful …