[HTML][HTML] A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

…, C Abraham, B Bauer, R Hasenbank, A Fritzsche… - Molecular cell, 2004 - cell.com
Abstract Analysis of protein-protein interactions (PPIs) is a valuable approach for characterizing
proteins of unknown function. Here, we have developed a strategy combining library and …

The rough endoplasmatic reticulum is a central nucleation site of siRNA‐mediated RNA silencing

…, L Sokol, D Trojer, J Wirz, J Hean, A Fritzsche… - The EMBO …, 2013 - embopress.org
Despite progress in mechanistic understanding of the RNA interference (RNAi) pathways, the
subcellular sites of RNA silencing remain under debate. Here we show that loading of lipid…

The impact of anxiety and depression on outcomes of pulmonary rehabilitation in patients with COPD

A von Leupoldt, K Taube, K Lehmann, A Fritzsche… - Chest, 2011 - Elsevier
Background Anxiety and depression are prevalent comorbidities in COPD and are related
to a worse course of disease. The present study examined the impact of anxiety and …

The approach-avoidance task as an online intervention in cigarette smoking: a pilot study

…, A Feist, BC Schneider, S Moritz, A Fritzsche - Journal of behavior …, 2015 - Elsevier
Background and objectives Dual-process models posit that addictive behaviors are
characterized by strong automatic processes that can be assessed with implicit measures. The …

[HTML][HTML] Effects of medical and psychological treatment of depression in patients with COPD–a review

A Fritzsche, A Clamor, A von Leupoldt - Respiratory medicine, 2011 - Elsevier
Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory lung disease
characterized by progressive and only partially reversible symptoms and by considerable …

Psychosocial factors and behavioral medicine interventions in asthma.

T Ritz, AE Meuret, AF Trueba, A Fritzsche… - Journal of Consulting …, 2013 - psycnet.apa.org
Objective: This review examines the evidence for psychosocial influences in asthma and
behavioral medicine approaches to its treatment. Method: We conducted a systematic review of …

Anticipation and experience of emotions in patients with schizophrenia and negative symptoms. An experimental study in a social context

M Engel, A Fritzsche, TM Lincoln - Schizophrenia research, 2016 - Elsevier
Negative symptoms play a central role in the impairment of social functioning in schizophrenia.
Healthy individuals use anticipated emotions to guide their decisions to seek out social …

[HTML][HTML] A novel multiplex cell viability assay for high-throughput RNAi screening

DF Gilbert, G Erdmann, X Zhang, A Fritzsche, K Demir… - PLoS …, 2011 - journals.plos.org
Cell-based high-throughput RNAi screening has become a powerful research tool in addressing
a variety of biological questions. In RNAi screening, one of the most commonly applied …

Validation of the German version of the clinical assessment interview for negative symptoms (CAINS)

M Engel, A Fritzsche, TM Lincoln - Psychiatry Research, 2014 - Elsevier
Validated assessment instruments could contribute to a better understanding and assessment
of negative symptoms and advance treatment research. The aim of this study was to …

Mental contrasting with implementation intentions increases goal-attainment in individuals with mild to moderate depression

A Fritzsche, B Schlier, G Oettingen… - Cognitive Therapy and …, 2016 - Springer
Depression is associated with difficulties initiating and performing goal-directed behavior. In
healthy participants, the self-regulation strategy of mental contrasting with implementation …