PURPOSE: Chronic obstructive pulmonary disease (COPD) impacts negatively on the quality
of life of patients. Several studies have shown that acute exacerbations (AEs) decrease …

Introduction: Chronic obstructive pulmonary disease (COPD) is a widespread disease. Sleep
quality is significantly impaired in many patients with COPD and may be further diminished …

PURPOSE: Acute exacerbations (AEs) have a negative impact on various aspects of the
progression of COPD, but objective and detailed data on the impact of hospitalizations for an …

Combined factors V and VIII deficiency is an autosomal recessive bleeding disorder associated
with plasma levels of coagulation factors V and VIII approximately 5% to 30% of normal. …

Background: Visceral leishmaniasis (VL) is an endemic in Southern Europe. However, details
regarding disease burden, clinical presentations, laboratory markers, management and …

Hemophilia A (HA) is an X-linked recessive disorder and the second most common coagulation
disorder with an incidence of 1 in 5,000 live born males. Worldwide, there are 178,500 …

Objective: To compare the effects of an isolated application of cervical spine thrust joint
manipulation vs. the application of cervical, cervico-thoracic junction and thoracic manipulation …

Objective— The relative balance between clot formation and fibrinolysis is considered to reflect
thrombotic potential following vascular injury. The aims of the present study were to (1) to …

Background Emerging evidence suggests that cervical and thoracic joint manipulations may
be advocated in treating patients with shoulder pain. Objectives To determine the acute …

Congenital factor deficiencies (CFDs) refer to inherited deficiency of coagulation factors in
the blood. A total of 481 patients with CFDs, who were diagnosed and followed at our …