User profiles for Andrew Nelson

Andrew Nelson

- Verified email at ansto.gov.au - Cited by 32742

Andrew T. Nelson

- Verified email at ornl.gov - Cited by 3940

Andrew Nelson

- Verified email at usace.army.mil - Cited by 3098

[HTML][HTML] SciPy 1.0: fundamental algorithms for scientific computing in Python

…, J Wilson, KJ Millman, N Mayorov, ARJ Nelson… - Nature …, 2020 - nature.com
SciPy is an open-source scientific computing library for the Python programming language.
Since its initial release in 2001, SciPy has become a de facto standard for leveraging …

Co-refinement of multiple-contrast neutron/X-ray reflectivity data using MOTOFIT

A Nelson - Journal of applied crystallography, 2006 - scripts.iucr.org
The contrast-variation technique is employed in multiple-contrast neutron/X-ray reflectometry
experiments to highlight scattering from different structural components that are present at a …

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

J Parrish-Novak, SR Dillon, A Nelson, A Hammond… - Nature, 2000 - nature.com
Cytokines are important in the regulation of haematopoiesis and immune responses, and can
influence lymphocyte development. Here we have identified a class I cytokine receptor that …

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing

AV Anzalone, XD Gao, CJ Podracky, AT Nelson… - Nature …, 2022 - nature.com
The targeted deletion, replacement, integration or inversion of genomic sequences could be
used to study or treat human genetic diseases, but existing methods typically require double…

[PDF][PDF] Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7

…, C McMurray, S Pandey, JP McKenna, A Nelson… - Cell reports, 2021 - cell.com
We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70
in multiple independent lineages, often occurring after acquisition of receptor binding motif …

LMFIT: Non-linear least-square minimization and curve-fitting for Python

…, M Rawlik, A Ingargiola, A Nelson - Astrophysics …, 2016 - ui.adsabs.harvard.edu
Lmfit provides a high-level interface to non-linear optimization and curve fitting problems for
Python. Lmfit builds on and extends many of the optimization algorithm of scipy. optimize, …

Ferritic/martensitic steels for next-generation reactors

RL Klueh, AT Nelson - Journal of nuclear materials, 2007 - Elsevier
Concepts for the next generation of nuclear power reactors designed to meet increasing
world-wide demand for energy include water-cooled, gas-cooled, and liquid-metal-cooled …

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

T Nakagawa, W Roth, P Wong, A Nelson, A Farr… - Science, 1998 - science.org
Degradation of invariant chain (Ii) is a critical step in major histocompatibility complex class II–restricted
antigen presentation. Cathepsin L was found to be necessary for Ii degradation …

T cell receptor δ gene mutant mice: independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

S Itohara, P Mombaerts, J Lafaille, J Iacomini, A Nelson… - Cell, 1993 - cell.com
T cells bearing T cell receptor (TCR) y and 6 chain heterodimers are first generated early in
ontogeny. They form distinct subsets that differ in their TCR rep ettoires and tissue distribution…

[HTML][HTML] Efficient prime editing in mouse brain, liver and heart with dual AAVs

…, GA Newby, X Wang, AV Anzalone, AT Nelson… - Nature …, 2024 - nature.com
Realizing the promise of prime editing for the study and treatment of genetic disorders
requires efficient methods for delivering prime editors (PEs) in vivo. Here we describe the …