Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations from deep phenotyping

AG Iglesias, AS Chiu, J Wong, P Campus… - Journal of …, 2023 - Soc Neuroscience
The survival of an organism is dependent on its ability to respond to cues in the environment.
Such cues can attain control over behavior as a function of the value ascribed to them. …

[HTML][HTML] The paraventricular thalamus as a critical node of motivated behavior via the hypothalamic-thalamic-striatal circuit

AG Iglesias, SB Flagel - Frontiers in integrative neuroscience, 2021 - frontiersin.org
In this review, we highlight evidence that supports a role for the paraventricular nucleus of the
thalamus (PVT) in motivated behavior. We include a neuroanatomical and neurochemical …

IFN-γ prevents TNF-α-induced apoptosis in C2C12 myotubes through down-regulation of TNF-R2 and increased NF-κB activity

L Tolosa, M Morlá, A Iglesias, X Busquets, J Lladó… - Cellular signalling, 2005 - Elsevier
Wasting of skeletal muscle (cachexia) is associated with a variety of chronic or inflammatory
disorders and has long been recognized as a poor prognostic sign. It is currently accepted …

Low-dose theophylline enhances the anti-inflammatory effects of steroids during exacerbations of COPD

BG Cosio, A Iglesias, A Rios, A Noguera, E Sala, K Ito… - Thorax, 2009 - thorax.bmj.com
Background: Chronic obstructive pulmonary disease (COPD) is characterised by an abnormal
inflammatory response mainly to cigarette smoke that flares up during exacerbations of …

Inhibition of a cortico-thalamic circuit attenuates cue-induced reinstatement of drug-seeking behavior in “relapse prone” male rats

…, P Campus, MS Klumpner, SE Chang, AG Iglesias… - …, 2022 - Springer
Rationale Relapse often occurs when individuals are exposed to stimuli or cues previously
associated with the drug-taking experience. The ability of drug cues to trigger relapse is …

B cell–activating factor. an orchestrator of lymphoid follicles in severe chronic obstructive pulmonary disease

…, M Laucho-Contreras, P Tejera, A Iglesias… - American journal of …, 2015 - atsjournals.org
Rationale: Patients with chronic obstructive pulmonary disease (COPD) have increased
pulmonary lymphoid follicle (LF) counts. B cell–activating factor of tumor necrosis factor family (…

[HTML][HTML] Predictive immunological, virological, and routine laboratory markers for critical COVID-19 on admission

…, N Martínez-Pomar, L Ramon-Clar, A Iglesias… - Canadian Journal of …, 2021 - hindawi.com
Background. Early identification of COVID-19 patients at risk of critical illness is a challenging
endeavor for clinicians. We aimed to establish immunological, virological, and routine …

Oral low-dose theophylline on top of inhaled fluticasone-salmeterol does not reduce exacerbations in patients with severe COPD: a pilot clinical trial

BG Cosío, H Shafiek, A Iglesias, A Yanez, R Córdova… - Chest, 2016 - Elsevier
Background COPD is characterized by chronic inflammation. In vitro and ex vivo observations
suggest that this inflammatory response is partially resistant to the effect of corticosteroids …

Mixed Th2 and non-Th2 inflammatory pattern in the asthma–COPD overlap: a network approach

LP de Llano, BG Cosío, A Iglesias… - … journal of chronic …, 2018 - Taylor & Francis
Introduction The asthma–chronic obstructive pulmonary disease (COPD) overlap (ACO) is a
clinical condition that combines features of those two diseases, and that is difficult to define …

[HTML][HTML] The role of IL-33/ST2 in COPD and its future as an antibody therapy

L Riera-Martínez, L Cànaves-Gómez, A Iglesias… - International journal of …, 2023 - mdpi.com
COPD is a leading cause of mortality and morbidity worldwide and is associated with a high
socioeconomic burden. Current treatment includes the use of inhaled corticosteroids and …