Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells

…, RT Christian, MP Horowitz, A Garcia… - Molecular cancer …, 2007 - AACR
Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during
cancer progression, and is the least understood genetically. Clinically, there are still limited …

Postoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre, open-label …

…, M Fernandez, A Fowler, A Garcia… - The lancet respiratory …, 2021 - thelancet.com
Background Respiratory complications are an important cause of postoperative morbidity.
We aimed to investigate whether continuous positive airway pressure (CPAP) administered …

Toward rigorous materials production: new approach methodologies have extensive potential to improve current safety assessment practices

…, S Dekkers, R Franken, W Fransman, A García‐Bilbao… - Small, 2020 - Wiley Online Library
Advanced material development, including at the nanoscale, comprises costly and complex
challenges coupled to ensuring human and environmental safety. Governmental agencies …

A role for MMP-10 (matrix metalloproteinase-10) in calcific aortic valve stenosis

…, J Ibarrola, V Arrieta, A García-Peña… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Aortic valve (AV) calcification plays an important role in the progression of aortic
stenosis (AS). MMP-10 (matrix metalloproteinase-10 or stromelysin-2) is involved in vascular …

COPD classification models and mortality prediction capacity

…, I Barrio, M Aburto, A García-Loizaga… - … journal of chronic …, 2019 - Taylor & Francis
Objective Our aim was to assess the impact of comorbidities on existing COPD prognosis
scores. Patients and methods A total of 543 patients with COPD (FEV 1 <80% and FEV 1 /FVC …

[HTML][HTML] Identification of a biomarker panel for colorectal cancer diagnosis

A García-Bilbao, R Armañanzas, Z Ispizua, B Calvo… - BMC cancer, 2012 - Springer
Background Malignancies arising in the large bowel cause the second largest number of
deaths from cancer in the Western World. Despite progresses made during the last decades, …

[HTML][HTML] Sex-differences in aortic stenosis: mechanistic insights and clinical implications

…, M Garaikoetxea, V Arrieta, A García-Peña… - Frontiers in …, 2022 - frontiersin.org
Objective: We aim to analyse sex-specific differences in aortic valves (AVs) and valve interstitial
cells (VICs) from aortic stenosis (AS) patients. Approach and Results: 238 patients with …

Galectin-3 down-regulates antioxidant peroxiredoxin-4 in human cardiac fibroblasts: a new pathway to induce cardiac damage

…, E Martinez-Martinez, A Garcia-Peña… - Clinical …, 2018 - portlandpress.com
Galectin-3 (Gal-3) is increased in heart failure (HF) and promotes cardiac fibrosis and
inflammation. We investigated whether Gal-3 modulates oxidative stress in human cardiac …

[HTML][HTML] Characterization of the sex-specific pattern of angiogenesis and lymphangiogenesis in aortic stenosis

…, JA Vico, V Arrieta, A García-Peña… - Frontiers in …, 2022 - frontiersin.org
Objective: We aim to analyse sex-related differences in angiogenesis and lymphangiogenesis
in aortic valves (AVs) and valve interstitial cells (VICs) from aortic stenosis (AS) patients. …

Soluble ST2 promotes oxidative stress and inflammation in cardiac fibroblasts: an in vitro and in vivo study in aortic stenosis

L Matilla, J Ibarrola, V Arrieta, A Garcia-Pena… - Clinical …, 2019 - portlandpress.com
Background: Soluble ST2 (interleukin 1 receptor-like 1) (sST2) is involved in inflammatory
diseases and increased in heart failure (HF). We herein investigated sST2 effects on oxidative …