Latent tuberculosis infection (LTBI) is characterised by the presence of immune responses
to previously acquired Mycobacterium tuberculosis infection without clinical evidence of …

Background The World Health Organization recommends the screening of all people living
with HIV for tuberculosis (TB) disease, followed by TB treatment, or isoniazid preventive …

Background There is a high incidence of opportunistic infection among HIV-1-infected patients
with tuberculosis in Africa and, consequently, high mortality. We assessed the safety and …

Background: Although failure of tuberculosis (TB) control in sub-Saharan Africa is attributed
to the HIV epidemic, it is unclear why the directly observed therapy short-course (DOTS) …

In the context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly
promoted, but concerns about the risk for development of isoniazid-resistant tuberculosis …

Background Tuberculosis is epidemic among workers in South African gold mines. We
evaluated an intervention to interrupt tuberculosis transmission by means of mass screening that …

Background In South Africa, sputum smear microscopy has been replaced with Xpert MTB/RIF
as the initial diagnostic test for tuberculosis. In a pragmatic parallel cluster-randomised …

Objective: To assess the performance of WHO clinical and CD4 cell count criteria for antiretroviral
treatment (ART) failure among HIV-infected adults in a workplace HIV care programme …

We hypothesized that rapid presentation may be a general feature of tuberculosis (TB)
associated with human immunodeficiency virus (HIV) that limits the impact of HIV on the point …

Background . Pneumocystis jirovecii pneumonia (PCP) remains the leading cause of
opportunistic infection among human immunodeficiency virus (HIV)– infected persons. Previous …