Elastic properties, Young's modulus determination and structural stability of the tropocollagen molecule: a computational study by steered molecular dynamics

AC Lorenzo, ER Caffarena - Journal of biomechanics, 2005 - Elsevier
The aim of this report is to investigate at microscopic level the elastic properties of a
tropocollagen-like molecule submitted to linear traction along its longitudinal axis. For this purpose, …

Lopinavir/ritonavir as single-drug therapy for maintenance of HIV-1 viral suppression: 48-week results of a randomized, controlled, open-label, proof-of-concept pilot …

…, F Pulido, R Delgado, A Lorenzo… - JAIDS Journal of …, 2005 - journals.lww.com
Objective: This study evaluated maintenance with lopinavir/ritonavir monotherapy vs.
continuing lopinavir/ritonavir and 2 nucleosides in HIV-infected patients with suppressed HIV …

Clinical presentation and short-and long-term outcomes in patients with isolated distal deep vein thrombosis vs proximal deep vein thrombosis in the RIETE registry

…, R López-Reyes, JB López-Sáez, A Lorenzo… - JAMA …, 2022 - jamanetwork.com
Importance Insufficient data exist about the clinical presentation, short-term, and long-term
outcomes of patients with isolated distal deep vein thrombosis (IDDVT), that is, thrombosis in …

[HTML][HTML] An acenocoumarol dosing algorithm using clinical and pharmacogenetic data in Spanish patients with thromboembolic disease

AM Borobia, R Lubomirov, E Ramírez, A Lorenzo… - PloS one, 2012 - journals.plos.org
Appropriate dosing of coumarins is difficult to establish, due to significant inter-individual
variability in the dose required to obtain stable anticoagulation. Several genetic and other …

[HTML][HTML] Effects of age on the risk of dying from pulmonary embolism or bleeding during treatment of deep vein thrombosis

…, H Bounameaux, JM Pedrajas, A Lorenzo… - Journal of vascular …, 2011 - Elsevier
BACKGROUND: The risk of patients dying of pulmonary embolism (PE) or bleeding during
the treatment of deep vein thrombosis (DVT), and whether these risks are influenced by …

Association between obstructive sleep apnea and pulmonary embolism

…, AG Suquia, C Fernández-Capitán, A Lorenzo… - Mayo Clinic …, 2013 - Elsevier
Objectives To compare the prevalence of obstructive sleep apnea (OSA) in patients with
pulmonary embolism (PE) with a sex-, age-, and body mass index (BMI)–matched, population-…

Predictors of post-thrombotic ulcer after acute DVT: the RIETE registry

…, V Rosa, M Barrón, A Lorenzo… - Thrombosis and …, 2018 - thieme-connect.com
In patients with deep-vein thrombosis (DVT) in the lower limbs, venous ulcer is the most
debilitating and end-stage clinical expression of the post-thrombotic syndrome (PTS). To date, …

Effect of excess weight and immune-related adverse events on the efficacy of cancer immunotherapy with anti-PD-1 antibodies

…, AI Ballesteros, R Arranz, A Lorenzo… - …, 2020 - Taylor & Francis
Immunotherapy is an effective treatment in advanced cancer, although predictors of
response are limited. We studied whether excess weight influences the efficacy outcomes of …

[HTML][HTML] Clinical outcomes during anticoagulant therapy in fragile patients with venous thromboembolism

…, P Di Micco, E Bucherini, A Lorenzo… - Research and practice …, 2017 - Elsevier
Lorenzo contributed to the interpretation of data, collected patients, and approved the final
version of the article. A. Villalobos contributed to the interpretation of data, collected patients, …

Pharmacokinetics of lopinavir/ritonavir in HIV/hepatitis C virus–coinfected subjects with hepatic impairment

…, SJK Causemaker, J Li, A Lorenzo… - The Journal of …, 2006 - Wiley Online Library
The effect of hepatic impairment on lopinavir/ritonavir pharmacokinetics was investigated.
Twenty‐four HIV‐1‐infected subjects received lopinavir 400 mg/ritonavir 100 mg twice daily …