[HTML][HTML] A preclinical rat model of heart failure with preserved ejection fraction with multiple comorbidities
G Hubesch, A Hanthazi, A Acheampong… - Frontiers in …, 2022 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) is a common complex clinical syndrome
for which there are currently few evidence-based therapies. As patients with HFpEF very …
for which there are currently few evidence-based therapies. As patients with HFpEF very …
Chemerin influences endothelin-and serotonin-induced pulmonary artery vasoconstriction in rats
A Hanthazi, P Jespers, G Vegh, GN Degroot… - Life sciences, 2019 - Elsevier
Aims Chemerin has been recently identified as a vasoactive adipokine implicated in blood
pressure regulation. In this context, we evaluated whether chemerin could influence …
pressure regulation. In this context, we evaluated whether chemerin could influence …
[HTML][HTML] Leptin-induced endothelium-independent vasoconstriction in thoracic aorta and pulmonary artery of spontaneously hypertensive rats: role of calcium …
…, P Jespers, OG Dilek, E Hupkens, A Hanthazi… - Plos one, 2017 - journals.plos.org
Decreased leptin-induced endothelium-dependent vasodilation has been reported in
spontaneously hypertensive rats (SHR). Here, we report leptin-induced vasoconstriction in …
spontaneously hypertensive rats (SHR). Here, we report leptin-induced vasoconstriction in …
[HTML][HTML] Chemerin added to endothelin-1 promotes rat pulmonary artery smooth muscle cell proliferation and migration
A Hanthazi, P Jespers, G Vegh, C Dubois… - Frontiers in …, 2020 - frontiersin.org
Background While chemerin has been shown to increase proliferation and migration of
systemic vascular smooth muscle cells (SMCs) contributing therefore to the development of …
systemic vascular smooth muscle cells (SMCs) contributing therefore to the development of …
Chemerin potentiates pulmonary artery reactivity to endothelin-1
A Hanthazi, S Gomart, CG Ménard, P Jespers… - 2015 - Eur Respiratory Soc
Background: The adipokine chemerin has been recently reported to increase aortic contractile
response to endothelin-1, which is a potent pulmonary vasoconstrictor. In the present …
response to endothelin-1, which is a potent pulmonary vasoconstrictor. In the present …
Chemerin alone or added to endothelin-1 stimulates rat pulmonary vascular smooth muscle cells proliferation, migration and resistance to apoptosis
A Hanthazi, P Jespers, G Vegh, C Dubois… - … CASCADES IN LUNG …, 2018 - atsjournals.org
Background: Proliferation, resistance to apoptosis and migration of pulmonary artery
smooth muscle cells (PASMCs) are characteristic pathogeneses of vascular remodeling in …
smooth muscle cells (PASMCs) are characteristic pathogeneses of vascular remodeling in …
Obesity-prone rats fed with high-fat diet as a model of HFpEF
G Hubesch, A Hanthazi, A Acheampong, C Watu… - Archives of …, 2021 - Elsevier
Heart failure with preserved ejection fraction (HFpEF) is a common and complex syndrome
with high mortality and morbidity rates for which there are currently no evidence-based …
with high mortality and morbidity rates for which there are currently no evidence-based …
Chemerin/CMKLR1 axis influences pulmonary arterial pressure and the NO signaling pathway
A Hanthazi, P Jespers, G Vegh, G Hubesch… - Archives of …, 2019 - Elsevier
Introduction Pulmonary arterial hypertension (PAH) is a clinical condition associated with
sustained elevations in pulmonary arterial pressure, leading to right ventricular failure. The …
sustained elevations in pulmonary arterial pressure, leading to right ventricular failure. The …
[PDF][PDF] Respective roles of genetic background and high fat diet in a rodent model of metabolic syndrome
G Hubesch, A Hanthazi, A Acheampong… - Archives of …, 2019 - academia.edu
Respective roles of genetic background and high fat diet in a rodent model of metabolic
syndrome Role of Connexin 43 increased e Page 1 Topic 6 - Hypertension 203 331 Respective …
syndrome Role of Connexin 43 increased e Page 1 Topic 6 - Hypertension 203 331 Respective …
[CITATION][C] Obese prone rats fed with high fat diet as a model of HFpEF
G Hubesch, A Hanthazi, A Acheampong… - 2021 - difusion.ulb.ac.be