User profiles for Ali Shamseddine

Ali Shamseddine

Professor of Hematology-Oncology, American University of Beirut Medical Center
Verified email at aub.edu.lb
Cited by 9725

Vascular endothelial growth factor family of ligands and receptors

ZK Otrock, JA Makarem, AI Shamseddine - Blood Cells, Molecules, and …, 2007 - Elsevier
VEGF signaling often represents a critical rate-limiting step in physiological angiogenesis.
The VEGF family comprises seven secreted glycoproteins that are designated VEGF-A, VEGF-…

Understanding the biology of angiogenesis: review of the most important molecular mechanisms

…, RAR Mahfouz, JA Makarem, AI Shamseddine - Blood Cells, Molecules …, 2007 - Elsevier
Angiogenesis is an important process for forming new blood vessels. It is fundamental in
many biological processes including development, reproduction and wound repair. Under …

2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19

…, J Santos, M Sebuhyan, A Shamseddine… - The Lancet …, 2022 - thelancet.com
The International Initiative on Thrombosis and Cancer is an independent academic working
group of experts aimed at establishing global consensus for the treatment and prophylaxis of …

2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer

…, S Saseedharan, A Shamseddine… - The Lancet …, 2019 - thelancet.com
Venous thromboembolism (VTE) is the second leading cause of death in patients with cancer.
These patients are at a high risk of VTE recurrence and bleeding during anticoagulant …

[HTML][HTML] Trends in epidemiology and management of breast cancer in developing Arab countries: a literature and registry analysis

…, F Geara, M Seoud, AI Shamseddine - International journal of …, 2007 - Elsevier
BACKGROUND: Registries and research on breast cancer in Arabic and developing countries
are limited. METHODS: We searched PubMed, Medline, WHO and IAEA publications, …

[HTML][HTML] Secondary bile acids: an underrecognized cause of colon cancer

H Ajouz, D Mukherji, A Shamseddine - World journal of surgical oncology, 2014 - Springer
Bile acids were first proposed as carcinogens in 1939. Since then, accumulated evidence
has linked exposure of cells of the gastrointestinal tract to repeated high physiologic levels of …

[HTML][HTML] Effects of young age at presentation on survival in breast cancer

…, ZK Salem, FB Geara, AI Shamseddine - BMC cancer, 2006 - Springer
Background Young age remains a controversial issue as a prognostic factor in breast cancer.
Debate includes patients from different parts of the world. Almost 50% of patients with …

[HTML][HTML] Resistance mechanisms to anti-angiogenic therapies in cancer

…, D Mukherji, S Temraz, A Shamseddine - Frontiers in …, 2020 - frontiersin.org
Tumor growth and metastasis rely on tumor vascular network for the adequate supply of
oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth factor …

Appendiceal mucinous neoplasms: diagnosis and management

WL Shaib, R Assi, A Shamseddine, OB Alese… - The …, 2017 - academic.oup.com
Objective Appendiceal mucinous neoplasms (AMNs) are a rare and heterogeneous disease
for which clinical management is challenging. We aim to review the literature regarding …

[HTML][HTML] Breast cancer in low-and middle-income countries: an emerging and challenging epidemic

A Tfayli, S Temraz, R Abou Mrad, A Shamseddine - Journal of …, 2010 - hindawi.com
Breast cancer is a major health care problem that affects more than one million women yearly.
While it is traditionally thought of as a disease of the industrialized world, around 45% of …