[HTML][HTML] Detecting laryngopharyngeal reflux in patients with upper airways symptoms: symptoms, signs or salivary pepsin?

A Spyridoulias, S Lillie, A Vyas, SJ Fowler - Respiratory medicine, 2015 - Elsevier
Background Laryngopharyngeal reflux (LPR) can induce laryngeal hyper-responsiveness, a
unifying feature underlying chronic cough and vocal cord dysfunction. The diagnosis of LPR …

Myxoedema coma in the setting of hyperglycaemic hyperosmolar state

A Spyridoulias, MS Riaz - Case Reports, 2016 - casereports.bmj.com
Decompensated hypothyroidism is a rare endocrine emergency but a differential that should
be considered in patients presenting critically unwell with systemic illness. We report a case …

Laryngopharyngeal pepsin reflux in chest clinic patients with upper airways symptoms

A Spyridoulias, S Lillie, J Haines, A Vyas, S Fowler - 2012 - Eur Respiratory Soc
Introduction: Laryngopharyngeal reflux (LPR) may underlie both chronic cough and vocal
cord dysfunction, and one explanation for a lack of response to standard anti-reflux therapy …

Hyperosmolar hyperglycaemic state causing atypical status epilepticus with hippocampal involvement

E Bartolini, R Valenti, JW Sander - Practical Neurology, 2022 - pn.bmj.com
Diabetes mellitus may arise abruptly and decompensate suddenly, leading to a hyperglycaemic
hyperosmolar state. Coma often ensues, although this usually reverses after the …

Detection of Pepsin in Oral Secretions of Infants with and without Laryngomalacia

MJ Klimara, TL Samuels, N Johnston… - Annals of Otology …, 2020 - journals.sagepub.com
Objectives: Laryngomalacia is a common cause of stridor in infants and is associated with
laryngopharyngeal reflux (LPR). Although pepsin in operative supraglottic lavage specimens …

[HTML][HTML] Laryngopharyngeal reflux: symptoms, signs, and presence of pepsin in saliva-a reliable diagnostic triad

S Divakaran, S Rajendran, RM Thomas… - International …, 2021 - thieme-connect.com
Introduction Twenty-four-hour multichannel intraluminal impedance with double probe pH
monitoring (MII-pH), though considered the most sensitive tool for the diagnosis of …

Gastroesophageal reflux and esophageal dysmotility in patients undergoing evaluation for lung transplantation: assessment, evaluation, and management

RB Yates, CA Pellegrini, BK Oelschlager - Lung Transplantation: Evolving …, 2018 - Springer
Gastroesophageal reflux disease (GERD) can dramatically affect quality of life but rarely
results in significant complications. Moreover, since GERD can be effectively managed with …

Assessing old and new diagnostic tests for gastroesophageal reflux disease

MF Vaezi, D Sifrim - Gastroenterology, 2018 - Elsevier
A detailed critique of objective measurements of gastroesophageal reflux disease (GERD)
would improve management of patients suspecting of having reflux, leading to rational …

Are multiple tests necessary for salivary pepsin detection in the diagnosis of laryngopharyngeal reflux?

J Wang, J Li, Q Nie, R Zhang - Otolaryngology–Head and …, 2022 - journals.sagepub.com
Objectives To evaluate the necessity of multiple salivary pepsin tests within a day when
diagnosing laryngopharyngeal reflux. Study Design Prospective cohort study. Setting Tertiary …

[HTML][HTML] GERD-related chronic cough: Possible mechanism, diagnosis and treatment

J Wu, Y Ma, Y Chen - Frontiers in Physiology, 2022 - frontiersin.org
GERD, or gastroesophageal reflux disease, is a prevalent medical condition that affects
millions of individuals throughout the world. Chronic cough is often caused by GERD, and …