User profiles for Ajay Verma
Ajay VermaCo-Founder and CEO, FVE Foundry Verified email at formationve.com Cited by 14169 |
Carbon monoxide: a putative neural messenger
A Verma, DJ Hirsch, CE Glatt, GV Ronnett, SH Snyder - Science, 1993 - science.org
Carbon monoxide, an activator of guanylyl cyclase, is formed by the action of the enzyme
heme oxygenase. By in situ hybridization in brain slices, discrete neuronal localization of …
heme oxygenase. By in situ hybridization in brain slices, discrete neuronal localization of …
[HTML][HTML] Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
H Lu, RA Forbes, A Verma - Journal of Biological Chemistry, 2002 - ASBMB
Cancer cells display high rates of aerobic glycolysis, a phenomenon known historically as
the Warburg effect. Lactate and pyruvate, the end products of glycolysis, are highly produced …
the Warburg effect. Lactate and pyruvate, the end products of glycolysis, are highly produced …
Poly (ADP-ribose) polymerase, nitric oxide and cell death
Poly (ADP-ribose) polymerase (PARP) is a nuclear enzyme that is activated by DNA strand
breaks to participate in DNA repair. Excessive activation of PARP, however, can deplete …
breaks to participate in DNA repair. Excessive activation of PARP, however, can deplete …
Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD
…, S Mehta, RCG Pollok, T Raine, PJ Smith, AM Verma… - Gut, 2021 - gut.bmj.com
Objective Delayed second dose SARS-CoV-2 vaccination trades maximal effectiveness for
a lower level of immunity across more of the population. We investigated whether patients …
a lower level of immunity across more of the population. We investigated whether patients …
Erythropoietin and erythropoietin receptor expression in human cancer
…, SM Beckwith, RL Pitts, E Clements, K Wong, A Verma - Cancer research, 2001 - AACR
Erythropoietin (EPO) stimulates the growth of erythroblasts in the bone marrow (C. Lacombe
and P. Mayeux, Nephrol. Dial. Transplant., 14 (Suppl. 2): 22–28, 1999). We report basal and …
and P. Mayeux, Nephrol. Dial. Transplant., 14 (Suppl. 2): 22–28, 1999). We report basal and …
[HTML][HTML] Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
…, A Mohyeldin, T McFate, AS Tait, A Verma - Journal of Biological …, 2005 - ASBMB
Continuous hydroxylation of the HIF-1 transcription factor α subunit by oxygen and 2-oxoglutarate-dependent
dioxygenases promotes decay of this protein and thus prevents the …
dioxygenases promotes decay of this protein and thus prevents the …
Neuropathology provides clues to the pathophysiology of Gaucher disease
K Wong, E Sidransky, A Verma, T Mixon… - Molecular genetics and …, 2004 - Elsevier
To better understand the pathogenesis of brain dysfunction in Gaucher disease (GD), we
studied brain pathology in seven subjects with type 1 GD (four also exhibited parkinsonism and …
studied brain pathology in seven subjects with type 1 GD (four also exhibited parkinsonism and …
Variable latency speculative addition: A new paradigm for arithmetic circuit design
Adders are one of the key components in arithmetic circuits. Enhancing their performance
can significantly improve the quality of arithmetic designs. This is the reason why the …
can significantly improve the quality of arithmetic designs. This is the reason why the …
[HTML][HTML] Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells
…, JA Califano, NH Jeoung, RA Harris, A Verma - Journal of Biological …, 2008 - ASBMB
High lactate generation and low glucose oxidation, despite normal oxygen conditions, are
commonly seen in cancer cells and tumors. Historically known as the Warburg effect, this …
commonly seen in cancer cells and tumors. Historically known as the Warburg effect, this …
Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor.
"Peripheral-type" benzodiazepine receptors are localized to the outer mitochondrial membrane.
We have identified potent competitive inhibitors of these receptors and purified them …
We have identified potent competitive inhibitors of these receptors and purified them …