Down-modulation of lung immune responses by interleukin-10 and transforming growth factor β (TGF-β) and analysis of TGF-β receptors I and II in active tuberculosis

…, J Geng, L Rego, LCO Lazzarini, AL Kritski… - Infection and …, 2004 - Am Soc Microbiol
Immune factors influencing progression to active tuberculosis (TB) remain poorly defined. In
this study, we investigated the expression of immunoregulatory cytokines and receptors by …

Tuberculosis is associated with a down-modulatory lung immune response that impairs Th1-type immunity

…, VC Flores, LR Pecanha, AL Kritski… - The Journal of …, 2009 - journals.aai.org
Immune mediators associated with human tuberculosis (TB) remain poorly defined. This
study quantified levels of lung immune mediator gene expression at the time of diagnosis and …

[HTML][HTML] Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosisclinical strains segregated by …

…, PEA da Silva, LS Fonseca, JL Ho, AL Kritski… - BMC microbiology, 2009 - Springer
Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in
Mycobacterium tuberculosisclinical strains segregated by spoligotype families from …

Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial

…, M Ram, MA Chaudhary, WR Bishai, AL Kritski… - The Lancet, 2009 - thelancet.com
Background New treatments are needed to shorten the time required to cure tuberculosis
and to treat drug-resistant strains. The fluoroquinolone moxifloxacin is a promising new agent …

Yield of sputum induction in the diagnosis of pleural tuberculosis

…, AL Reingold, CL Daley, AL Kritski - American journal of …, 2003 - atsjournals.org
We prospectively evaluated the diagnostic yield of acid-fast bacilli smear and culture for
Mycobacterium tuberculosis using sputum induction (SI) in the workup of patients with …

Application of sensitive and specific molecular methods to uncover global dissemination of the major RDRio Sublineage of the Latin American-Mediterranean …

…, T Zozio, C Sola, SM Spindola, AL Kritski… - Journal of clinical …, 2008 - Am Soc Microbiol
The Latin American-Mediterranean (LAM) family of Mycobacterium tuberculosis is believed
to be the cause of ∼15% of tuberculosis cases worldwide. Previously, we defined a …

Comparison of sputum induction with fiberoptic bronchoscopy in the diagnosis of tuberculosis: experience at an acquired immune deficiency syndrome reference …

…, AL Reingold, CL Daley, AL Kritski - American journal of …, 2000 - atsjournals.org
Many patients with suspected pulmonary tuberculosis (PTB) do not produce sputum
spontaneously or are smear-negative for acid-fast bacilli (AFB). We prospectively compared the …

[HTML][HTML] Transcriptomic Biomarkers for Tuberculosis: Evaluation of DOCK9. EPHA4, and NPC2 mRNA Expression in Peripheral Blood

…, AS De Almeida, ASR Moreira, AL Kritski… - Frontiers in …, 2016 - frontiersin.org
Lately, much effort has been made to find mRNA biomarkers for tuberculosis (TB) disease/infection
with microarray-based approaches. In a pilot investigation, through RNA sequencing …

TheMycobacterium tuberculosis Complex-Restricted Genecfp32 Encodes an Expressed Protein That Is Detectable inTuberculosis Patients and Is Positively …

…, E Shashkina, S Laal, MB Conde, AL Kritski… - Infection and …, 2003 - Am Soc Microbiol
Human tuberculosis (TB) is caused by the bacillus Mycobacteriumtuberculosis, a subspecies
of the M. tuberculosis complex (MTC) of mycobacteria. Postgenomic dissection of the M. …

Transmission of tuberculosis to close contacts of patients with multidrug-resistant tuberculosis.

AL Kritski, MJ Marques, MF Rabahi… - American journal of …, 1996 - atsjournals.org
Multidrug-resistant tuberculosis (MDRTB) has emerged as a major public health problem
worldwide. To determine the incidence and risk factors associated with tuberculosis among …