Role of oxygen free radicals in cancer development

D Dreher, AF Junod - European Journal of cancer, 1996 - Elsevier
In aerobic life, oxidative stress arises from both endogenous and exogenous sources.
Despite antioxidant defence mechanisms, cell damage from oxygen free radicals (OFR) is …

Predicting adverse outcome in patients with acute pulmonary embolism: a risk score

…, H Bounameaux, AF Junod - Thrombosis and …, 2000 - thieme-connect.com
Reliable prediction of adverse outcomes in acute pulmonary embolism may help choose
between in-hospital and ambulatory treatment. We aimed to identify predictors of adverse …

Assessing clinical probability of pulmonary embolism in the emergency ward: a simple score

J Wicki, TV Perneger, AF Junod… - Archives of internal …, 2001 - jamanetwork.com
Objective To develop a simple standardized clinical score to stratify emergency ward patients
with clinically suspected pulmonary embolism (PE) into groups with a high, intermediate, …

Prospective evaluation of patients with syncope: a population-based study

…, JT Metzger, C Lovis, PF Unger, AF Junod - The American journal of …, 2001 - Elsevier
… or symptomatic (syncope or presyncope) sinus pause ≥2 seconds; sinus bradycardia ≤35
beats per minute or symptomatic bradycardia ≤40 beats per minute; atrial fibrillation with …

Role of echocardiography in the evaluation of syncope: a prospective study

FP Sarasin, AF Junod, D Carballo, S Slama, PF Unger… - Heart, 2002 - heart.bmj.com
AF Junod1, … A 12 lead ECG was considered abnormal in the presence of any non-diagnostic
findings (for example, atrial fibrillation, repetitive premature ventricular contractions, or …

Hydrogen peroxide-induced DNA damage is independent of nuclear calcium but dependent on redox-active ions

L Jornot, H Petersen, AF JUNOD - Biochemical Journal, 1998 - portlandpress.com
In cells undergoing oxidative stress, DNA damage may result from attack by • OH radicals
produced by the Fenton reaction, and/or by nucleases activated by nuclear calcium. In the …

Prevalence of orthostatic hypotension among patients presenting with syncope in the ED

…, D Carballo, S Slama, AF Junod… - The American journal of …, 2002 - Elsevier
We sought to determine the prevalence of orthostatic hypotension as a cause of syncope in
the emergency setting, and describe the characteristics of patients diagnosed with this …

Predictors of inappropriate hospital days in a department of internal medicine

…, PF Unger, FA Waidvogela, AF Junod - International journal …, 1998 - academic.oup.com
Background This study aimed to identify predictors of inappropriate hospital days in a
deparUnent of internal medicine, as a basis for quality improvement interventions. Methods The …

Differential effects of superoxide, hydrogen peroxide, and hydroxyl radical on intracellular calcium in human endothelial cells

D Dreher, AF Junod - Journal of cellular physiology, 1995 - Wiley Online Library
… for 1 h) on cellular protein and DNA content, but the elimination of 0,- with SOD only partially
restored protein content and afforded no protection against DNA damage (Ody and Junod, …

Mode of presentation and diagnosis of bacterial pneumonia in human immunodeficiency virus-infected patients

…, LP Nicod, R Auckenthaler, AF Junod - Am Rev Respir …, 1991 - atsjournals.org
Bacterial pneumonia (BP) has recently been reported to be more frequent in human
immunodeficiency virus (HIV)-Infected patients than in normal hosts. This study reviews the clinical …