Health effects of quercetin: from antioxidant to nutraceutical

AW Boots, GRMM Haenen, A Bast - European journal of pharmacology, 2008 - Elsevier
Quercetin, a member of the flavonoids family, is one of the most prominent dietary antioxidants.
It is ubiquitously present in foods including vegetables, fruit, tea and wine as well as …

The versatile use of exhaled volatile organic compounds in human health and disease

AW Boots, JJBN van Berkel, JW Dallinga… - Journal of breath …, 2012 - iopscience.iop.org
Exhaled breath contains thousands of volatile organic compounds (VOCs) of which the
composition varies depending on health status. Various metabolic processes within the body …

Oxidant metabolism in chronic obstructive pulmonary disease

AW Boots, G Haenen, A Bast - European Respiratory Journal, 2003 - Eur Respiratory Soc
The development and progression of chronic obstructive pulmonary disease (COPD) have
been associated with increased oxidative stress or reduced antioxidant resources. Several …

SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

…, T Muley, H Winter, M Meister, C Veith, AW Boots… - The EMBO …, 2020 - embopress.org
The SARS ‐CoV‐2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID ‐19 …

A European Respiratory Society technical standard: exhaled biomarkers in lung disease

…, B Antus, E Baraldi, A Bikov, AW Boots… - European …, 2017 - Eur Respiratory Soc
Breath tests cover the fraction of nitric oxide in expired gas (F ENO ), volatile organic compounds
(VOCs), variables in exhaled breath condensate (EBC) and other measurements. For …

Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells

K Gerloff, C Albrecht, AW Boots, I Förster… - …, 2009 - Taylor & Francis
The use of engineered nanoparticles in the food sector is anticipated to increase dramatically,
whereas their potential hazards for the gastrointestinal tract are still largely unknown. We …

In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers

AW Boots, LC Wilms, ELR Swennen, JCS Kleinjans… - Nutrition, 2008 - Elsevier
OBJECTIVE: Quercetin, a commonly occurring flavonoid and well known antioxidant, has
been suggested to possess other beneficial activities. The present study investigated the …

The quercetin paradox

AW Boots, H Li, RPF Schins, R Duffin… - Toxicology and Applied …, 2007 - Elsevier
Free radical scavenging antioxidants, such as quercetin, are chemically converted into
oxidation products when they protect against free radicals. The main oxidation product of …

[HTML][HTML] Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis

AW Boots, M Drent, VCJ de Boer, A Bast… - Clinical nutrition, 2011 - Elsevier
BACKGROUND & AIMS: Oxidative stress and low antioxidant levels are implicated in the
aetiology of sarcoidosis, an inflammatory disease. Quercetin is a potent dietary antioxidant that …

Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation

AW Boots, N Kubben, GRMM Haenen, A Bast - … and biophysical research …, 2003 - Elsevier
When an antioxidant scavenges a reactive species, ie, when it exerts its antioxidant activity,
the antioxidant is converted into potentially harmful oxidation products. In this way, the …