[HTML][HTML] Diagnosis and management of spinal muscular atrophy: Part 1: Recommendations for diagnosis, rehabilitation, orthopedic and nutritional care
…, E Bertini, RH Davis, OH Meyer, AK Simonds… - Neuromuscular …, 2018 - Elsevier
Spinal muscular atrophy (SMA) is a severe neuromuscular disorder due to a defect in the
survival motor neuron 1 (SMN1) gene. Its incidence is approximately 1 in 11,000 live births. In …
survival motor neuron 1 (SMN1) gene. Its incidence is approximately 1 in 11,000 live births. In …
Consensus statement on standard of care for congenital muscular dystrophies
…, C Sewry, K Storhaug, A Simonds… - Journal of child …, 2010 - journals.sagepub.com
Congenital muscular dystrophies are a group of rare neuromuscular disorders with a wide
spectrum of clinical phenotypes. Recent advances in understanding the molecular …
spectrum of clinical phenotypes. Recent advances in understanding the molecular …
Noninvasive ventilation for chest wall and neuromuscular disorders
JM Shneerson, AK Simonds - European Respiratory Journal, 2002 - Eur Respiratory Soc
Neuromuscular and chest wall disorders are individually uncommon but together form an
important group of conditions that can lead to chronic ventilatory failure. This is best …
important group of conditions that can lead to chronic ventilatory failure. This is best …
Effect of noninvasive respiratory strategies on intubation or mortality among patients with acute hypoxemic respiratory failure and COVID-19: the RECOVERY-RS …
…, SE Regan, C Ross, AJ Rostron, M Saim, AK Simonds… - Jama, 2022 - jamanetwork.com
Importance Continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO)
have been recommended for acute hypoxemic respiratory failure in patients with COVID-19…
have been recommended for acute hypoxemic respiratory failure in patients with COVID-19…
Consensus statement for standard of care in spinal muscular atrophy
…, ES Bertini, M Schroth, A Simonds… - Journal of child …, 2007 - journals.sagepub.com
Spinal muscular atrophy is a neurodegenerative disease that requires multidisciplinary
medical care. Recent progress in the understanding of molecular pathogenesis of spinal …
medical care. Recent progress in the understanding of molecular pathogenesis of spinal …
[HTML][HTML] Adaptive servo-ventilation for central sleep apnea in systolic heart failure
Background Central sleep apnea is associated with poor prognosis and death in patients
with heart failure. Adaptive servo-ventilation is a therapy that uses a noninvasive ventilator to …
with heart failure. Adaptive servo-ventilation is a therapy that uses a noninvasive ventilator to …
Patterns of home mechanical ventilation use in Europe: results from the Eurovent survey
…, D Robert, B Schoenhofer, AK Simonds… - European respiratory …, 2005 - Eur Respiratory Soc
The study was designed to assess the patterns of use of home mechanical ventilation (HMV)
for patients with chronic respiratory failure across Europe. A detailed questionnaire of …
for patients with chronic respiratory failure across Europe. A detailed questionnaire of …
[PDF][PDF] Spatiotemporal analysis of human intestinal development at single-cell resolution
Development of the human intestine is not well understood. Here, we link single-cell RNA
sequencing and spatial transcriptomics to characterize intestinal morphogenesis through time. …
sequencing and spatial transcriptomics to characterize intestinal morphogenesis through time. …
Increased amygdala and insula activation during emotion processing in anxiety-prone subjects
Objective: Increased amygdala reactivity during processing of certain types of emotional
stimuli (eg, fear, anger) has been observed in patients with anxiety disorders such as social …
stimuli (eg, fear, anger) has been observed in patients with anxiety disorders such as social …
Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness
…, AH Nickol, MI Polkey, AK Simonds - European …, 2003 - Eur Respiratory Soc
Adults and children with neuromuscular disease exhibit weak cough and are susceptible to
recurrent chest infections, a major cause of morbidity and mortality. Mechanical insufflation/…
recurrent chest infections, a major cause of morbidity and mortality. Mechanical insufflation/…