[HTML][HTML] Asthma: from bronchoconstriction to airways inflammation and remodeling
…, WW Busse, M Johnson, AM Vignola - American journal of …, 2000 - atsjournals.org
… In interstitial lung diseases, AM were found to be activated and to release cytokines,
plasminogen activator, and a fibrinolytic inhibitor (246-248) as well as MIP-1α, a peptide with …
plasminogen activator, and a fibrinolytic inhibitor (246-248) as well as MIP-1α, a peptide with …
Links between rhinitis and asthma
J Bousquet, AM Vignola, P Demoly - Allergy, 2003 - Wiley Online Library
There is compelling evidence of a close relationship between the upper and lower airways
in asthma and rhinitis. Rhinitis is present in the majority of patients with asthma, and a …
in asthma and rhinitis. Rhinitis is present in the majority of patients with asthma, and a …
Airway remodeling in asthma
AM Vignola, F Mirabella, G Costanzo, R Di Giorgi… - Chest, 2003 - Elsevier
… Evidence suggests that the number and size of bronchial vessels is moderately increased
in patients with asthma compared with normal controls (for a review, see Vignola et al 1 and …
in patients with asthma compared with normal controls (for a review, see Vignola et al 1 and …
Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis
AM Vignola, P Chanez, G Chiappara… - American journal of …, 1997 - atsjournals.org
We assessed whether transforming growth factor- β (TGF- β ), a fibrogenic growth factor, may
be involved in remodeling of asthma and chronic bronchitis; its expression was compared …
be involved in remodeling of asthma and chronic bronchitis; its expression was compared …
Efficacy and tolerability of anti‐immunoglobulin E therapy with omalizumab in patients with concomitant allergic asthma and persistent allergic rhinitis: SOLAR
AM Vignola, M Humbert, J Bousquet, LP Boulet… - Allergy, 2004 - Wiley Online Library
Background: Anti‐IgE therapy could be particularly beneficial for patients with concomitant
disease as it targets a common factor in both diseases. The aim of this study was to evaluate …
disease as it targets a common factor in both diseases. The aim of this study was to evaluate …
Sputum metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio correlates with airflow obstruction in asthma and chronic bronchitis
AM Vignola, L Riccobono, A Mirabella… - American journal of …, 1998 - atsjournals.org
… The slides were read by two independent investigators (PD, AM) blindly who counted at
least 400 cells per slide. The number of the squamous cells was subtracted from the total cell …
least 400 cells per slide. The number of the squamous cells was subtracted from the total cell …
Airway inflammation in mild intermittent and in persistent asthma
AM Vignola, P Chanez, AM Campbell… - American journal of …, 1998 - atsjournals.org
The severity of asthma can be graded from mild intermittent to severe persistent. Airway
inflammation is a feature of persistent asthma. We compared several markers of inflammation in …
inflammation is a feature of persistent asthma. We compared several markers of inflammation in …
[HTML][HTML] Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma
…, D Olivieri, E Pozzi, N Crimi, AM Vignola… - … England Journal of …, 2007 - Mass Medical Soc
Background Treatment guidelines recommend the regular use of inhaled corticosteroids for
patients with mild persistent asthma. We investigated whether the symptom-driven use of a …
patients with mild persistent asthma. We investigated whether the symptom-driven use of a …
Standard skin prick testing and sensitization to inhalant allergens across Europe – a survey from the GA2LEN network*
…, J Ring, P Schmid‐Grendelmeier, AM Vignola… - Allergy, 2005 - Wiley Online Library
Skin prick testing (SPT) is the standard method for diagnosing allergic sensitization but is to
some extent performed differently in clinical centres across Europe. There would be …
some extent performed differently in clinical centres across Europe. There would be …
Corticosteroid reversibility in COPD is related to features of asthma.
P Chanez, AM Vignola, T O'Shaugnessy… - American journal of …, 1997 - atsjournals.org
Eosinophilic inflammation has been observed in the airways of patients with chronic obstructive
pulmonary disease (COPD). A subset of patients clinically diagnosed as having COPD …
pulmonary disease (COPD). A subset of patients clinically diagnosed as having COPD …