Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression
…, AJ Van Wijnen, JL Stein, M Montecino, A Javed… - Oncogene, 2004 - nature.com
We present an overview of Runx involvement in regulatory mechanisms that are requisite
for fidelity of bone cell growth and differentiation, as well as for skeletal homeostasis and the …
for fidelity of bone cell growth and differentiation, as well as for skeletal homeostasis and the …
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors
Formation of skeletal elements during embryogenesis and the dynamic remodeling of bone
in the adult involve an exquisite interplay of developmental cues, signaling proteins, …
in the adult involve an exquisite interplay of developmental cues, signaling proteins, …
Networks and hubs for the transcriptional control of osteoblastogenesis
JB Lian, GS Stein, A Javed, AJ Van Wijnen… - Reviews in Endocrine …, 2006 - Springer
We present an overview of the concepts of tissue-specific transcriptional control mechanisms
essential for development of the bone cell phenotype. BMP2 induced transcription factors …
essential for development of the bone cell phenotype. BMP2 induced transcription factors …
[HTML][HTML] Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression
…, RA Bhat, PVN Bodine, BS Komm, A Javed… - Journal of Biological …, 2005 - ASBMB
Both activating and null mutations of proteins required for canonical WNT signaling have
revealed the importance of this pathway for normal skeletal development. However, tissue-…
revealed the importance of this pathway for normal skeletal development. However, tissue-…
Mapping vulnerability to multiple stressors: climate change and globalization in India
…, H Venema, G Aandahl, H Tompkins, A Javed… - Global environmental …, 2004 - Elsevier
There is growing recognition in the human dimensions research community that climate
change impact studies must take into account the effects of other ongoing global changes. Yet …
change impact studies must take into account the effects of other ongoing global changes. Yet …
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer
Pancreatic cancer is the most lethal common solid malignancy. Systemic therapies are often
ineffective, and predictive biomarkers to guide treatment are urgently needed. We …
ineffective, and predictive biomarkers to guide treatment are urgently needed. We …
Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers
The earlier diagnosis of cancer is one of the keys to reducing cancer deaths in the future. Here
we describe our efforts to develop a noninvasive blood test for the detection of pancreatic …
we describe our efforts to develop a noninvasive blood test for the detection of pancreatic …
[PDF][PDF] Impact of employee motivation on employee performance
I Shahzadi, A Javed, SS Pirzada, S Nasreen… - European Journal of …, 2014 - core.ac.uk
Employee motivation is considered as a force that drives the employees toward attaining
specific goals and objectives of the organization. Now days, it is one of the sizzling issue in …
specific goals and objectives of the organization. Now days, it is one of the sizzling issue in …
[HTML][HTML] Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling
CH Byon, A Javed, Q Dai, JC Kappes… - Journal of Biological …, 2008 - ASBMB
Oxidative stress plays a critical role in the pathogenesis of atherosclerosis including the
formation of lipid laden macrophages and the development of inflammation. However, oxidative …
formation of lipid laden macrophages and the development of inflammation. However, oxidative …
Future smart cities: Requirements, emerging technologies, applications, challenges, and future aspects
Future smart cities are the key to fulfilling the ever-growing demands of citizens. Information
and communication advancements will empower better administration of accessible …
and communication advancements will empower better administration of accessible …