In recent years, there has been increased interest in the vascular component of airway
remodelling in chronic bronchial inflammation, such as asthma and COPD, and in its role in the …

Background Some patients with severe asthma have frequent exacerbations associated with
persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled …

Mucociliary clearance (MCC) is one of the most importantnonspecific defense mechanisms
of the respiratory tract, and itsimpairment is a well-documented feature of chronic …

Interstitial lung diseases (ILDs) are functionally characterized by a restrictive ventilatory defect
due to a reduced distensibility of the lung parenchyma. ILD patients also show a reduced …

In 102 healthy Caucasians, 20–50 years old, we investigated the effect of anthropometrics
on the 6-min walk test (6MWT), in order to provide reference values for walk distance (6MWD), …

Background: The impact of short-term preoperative pulmonary rehabilitation on exercise
capacity of patients with chronic obstructive pulmonary disease undergoing lobectomy for non-…

Background There is increasing in vitro evidence to support a role for vascular endothelial
growth factor (VEGF), a major regulator of angiogenesis, as a mediator of fibrosis associated …

We conducted a randomized, double-blind, parallel-group study to assess the effect of 6
weeks treatment with low-dose (100 μg twice a day) or high-dose (500 μg twice a day) inhaled …

Background: Sex differences have been demonstrated in the acute phase of coronavirus
disease 2019 (COVID-19). Women (F) were found to be less prone to develop a severe …

Purpose Airways remodeling, evaluated as the subepithelial layer thickness, was compared
in asthmatic patients with that of healthy subjects, and was related to clinical grading of …