Introduction On March 11, 2020, the World Health Organization sounded the COVID-19
pandemic alarm. While efforts in the first few months focused on reducing the mortality of infected …

Rationale: Identification of risk factors for lung cancer can help in selecting patients who may
benefit the most from smoking cessation interventions, early detection, or chemoprevention. …

Importance COVID‐19 is caused by SARS‐CoV‐2, a betacoronavirus that uses the
angiotensin‐converting enzyme‐related carboxypeptidase (ACE2) receptor to gain entry into cells. …

… Dr Alcaide: contributed to the writing of the manuscript and statistical analysis. … Drs de
Torres, Alcaide, Lozano, and Bastarrika, and Ms Lacunza have reported that no potential conflicts …

Multimorbidity frequently affects the ageing population and their co-existence may not occur
at random. Understanding their interactions and that with clinical variables could be …

Rationale: Lung cancer screening using computed tomography (CT) is effective in detecting
lung cancer in early stages. Concerns regarding false-positive rates and unnecessary …

Rationale: Patients with chronic obstructive pulmonary disease (COPD) are at high risk for
lung cancer (LC) and represent a potential target to improve the diagnostic yield of screening …

Leptin is a powerful stimulant of ventilation in rodents. In humans, resistance to leptin has
been consistently associated with obesity. Raised leptin levels have been reported in subjects …

Rationale: Lung cancer (LC) screening using low-dose chest computed tomography is now
recommended in several guidelines using the National Lung Screening Trial (NLST) entry …

Introduction and objectives European experience regarding lung cancer screening using
low-dose chest CT (LDCT) is available. However, there is limited data on the Spanish …