Meta-analysis and imputation refines the association of 15q25 with smoking quantity

…, P McGuffin, R Day, K Matthews, P Bakke, A Gulsvik… - Nature …, 2010 - nature.com
Smoking is a leading global cause of disease and mortality 1 . We established the Oxford-GlaxoSmithKline
study (Ox-GSK) to perform a genome-wide meta-analysis of SNP association …

Variants in FAM13A are associated with chronic obstructive pulmonary disease

…, R Tal-Singer, DA Lomas, P Bakke, A Gulsvik… - Nature …, 2010 - nature.com
We performed a genome-wide association study for chronic obstructive pulmonary disease (COPD)
in three population cohorts, including 2,940 cases and 1,380 controls who were …

Gender differences in COPD: are women more susceptible to smoking effects than men?

IC Sørheim, A Johannessen, A Gulsvik, PS Bakke… - Thorax, 2010 - thorax.bmj.com
Background The number of female smokers developing chronic obstructive pulmonary disease
(COPD) is rapidly increasing, but whether or not there exists a differential susceptibility …

International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study

…, TA Lee, KB Weiss, RL Jensen, GB Marks, A Gulsvik… - The Lancet, 2007 - thelancet.com
Background Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity
and mortality worldwide, and accurate estimates of the prevalence of this disease are …

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

…, RG Barr, D Sparrow, AA Litonjua, P Bakke, A Gulsvik… - Nature …, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide 1 .
We performed a genetic association study in 15,256 cases and 47,936 controls, with …

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

…, F Dudbridge, R Ewert, C Gieger, A Gulsvik… - Nature …, 2019 - nature.com
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …

The cost of persistent asthma in Europe: an international population-based study in adults

…, MW Gerbase, D Gislason, A Gulsvik… - International archives of …, 2012 - karger.com
Background: This study is aimed at providing a real-world evaluation of the economic cost
of persistent asthma among European adults according to the degree of disease control [as …

Comparison of spirometry criteria for the diagnosis of COPD: results from the BOLD study

…, P Burney, PL Enright, A Gulsvik… - European …, 2009 - Eur Respiratory Soc
Published guidelines recommend spirometry to accurately diagnose chronic obstructive
pulmonary disease (COPD). However, even spirometry-based COPD prevalence estimates can …

Higher dosage nicotine patches increase one-year smoking cessation rates: results from the European CEASE trial. Collaborative European Anti-Smoking Evaluation …

…, MA Russell, R Saracci, A Gulsvik… - European …, 1999 - Eur Respiratory Soc
The Collaborative European Anti-Smoking Evaluation (CEASE) was a European multicentre,
randomized, double-blind placebo controlled smoking cessation study. The objectives …

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

…, BD Hobbs, AA Litonjua, DW Sparrow, A Gulsvik… - Nature …, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association discovery …