A pharmacological review of selective oestrogen receptor modulators

SR Goldstein, S Siddhanti, AV Ciaccia… - Human reproduction …, 2000 - academic.oup.com
Selective oestrogen receptor modulators (SERMs) are structurally diverse non-steroidal
compounds that bind to oestrogen receptors and produce oestrogen agonist effects in some …

CD8+ T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease

…, CE Mapp, P Maestrelli, A Ciaccia… - American journal of …, 1998 - atsjournals.org
To investigate whether the inflammatory process in peripheral airways is different in
smokers who develop symptoms of chronic bronchitis and chronic airflow limitation and in …

Airway eosinophilia in chronic bronchitis during exacerbations.

…, P Calcagni, CE Mapp, A Ciaccia… - American journal of …, 1994 - atsjournals.org
To examine the nature and the degree of airway inflammation in chronic bronchitis during
exacerbations, bronchial biopsies and sputum were obtained in 11 subjects with chronic …

Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease

…, K Busljetic, G Turato, G Ligabue, A Ciaccia… - American journal of …, 2003 - atsjournals.org
To determine whether patients with fixed airflow obstruction have distinct pathologic and
functional characteristics depending on a history of either asthma or chronic obstructive …

[HTML][HTML] Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis

DE Joyce, L Gelbert, A Ciaccia, B DeHoff… - Journal of Biological …, 2001 - ASBMB
Human protein C is a natural anticoagulant factor, and a recombinant activated form of the
molecule (rhAPC) is completing clinical evaluation for treatment of severe sepsis. Because of …

Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis

…, A Ferraresso, R Drigo, A Potena, A Ciaccia… - American review of …, 1993 - atsjournals.org
To examine the nature and the degree of leukocyte infiltration and to determine the state of
activation of cells in bronchial mucosa of subjects with chronic bronchitis, bronchoscopy was …

CD8+ ve cells in the lungs of smokers with chronic obstructive pulmonary disease

…, CE Mapp, P Maestrelli, A Ciaccia… - American journal of …, 1999 - atsjournals.org
Previous studies have shown an increased number of inflammatory cells and, in particular,
CD8 + ve cells in the airways of smokers with chronic obstructive pulmonary disease (COPD). …

Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease

…, I GUZZINATI, M Saetta, A CIACCIA… - American journal of …, 2000 - atsjournals.org
We investigated the relationship between the reversibility of airflow limitation, the concentration
of nitric oxide (NO) in exhaled air, and the inflammatory cells in the sputum of patients …

COPD increases the risk of squamous histological subtype in smokers who develop non-small cell lung carcinoma

…, G Cavallesco, E Forini, M Saetta, A Ciaccia… - Thorax, 2004 - thorax.bmj.com
Background: Squamous cell carcinoma has a stronger association with tobacco smoking than
other non-small cell lung cancers (NSCLC). A study was undertaken to determine whether …

Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations

…, KF Chung, PJ Barnes, IM Adcock, A Ciaccia… - Thorax, 2003 - thorax.bmj.com
Background: Exacerbations represent an important feature of the clinical manifestation and
natural history of chronic obstructive pulmonary disease (COPD). Nuclear localisation of p65 …