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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1995 1
1997 2
1998 1
1999 1
2000 2
2001 3
2002 4
2004 4
2005 3
2006 1
2007 3
2008 2
2009 3
2010 3
2011 2
2013 3
2014 1
2016 2
2017 3
2018 1
2019 1
2020 2
2021 4
2022 2
2023 1
2024 0

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52 results

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Page 1
Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis.
Hayes AJ, Zheng X, O'Kelly J, Neyton LPA, Bochkina NA, Uings I, Liddle J, Baillie JK, Just G, Binnie M, Homer NZM, Murray TBJ, Baily J, McGuire K, Skouras C, Garden OJ, Webster SP, Iredale JP, Howie SEM, Mole DJ. Hayes AJ, et al. Among authors: uings i. Cell Rep. 2023 Aug 29;42(8):112763. doi: 10.1016/j.celrep.2023.112763. Epub 2023 Jul 19. Cell Rep. 2023. PMID: 37478012 Free article.
Development of IL-5 receptor antagonists.
Uings I, McKinnon M. Uings I, et al. Curr Pharm Des. 2002;8(20):1837-44. doi: 10.2174/1381612023393800. Curr Pharm Des. 2002. PMID: 12171535 Review.
Cell receptors and cell signalling.
Uings IJ, Farrow SN. Uings IJ, et al. Mol Pathol. 2000 Dec;53(6):295-9. doi: 10.1136/mp.53.6.295. Mol Pathol. 2000. PMID: 11193047 Free PMC article. Review.
Designing corticosteroid drugs for pulmonary selectivity.
Biggadike K, Uings I, Farrow SN. Biggadike K, et al. Among authors: uings i. Proc Am Thorac Soc. 2004;1(4):352-5. doi: 10.1513/pats.200409-048TA. Proc Am Thorac Soc. 2004. PMID: 16113457 Review.
The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding.
Liddle J, Pearce AC, Arico-Muendel C, Belyanskaya S, Brewster A, Brown M, Chung CW, Denis A, Dodic N, Dossang A, Eddershaw P, Klimaszewska D, Haq I, Holmes DS, Jagger A, Jakhria T, Jigorel E, Lind K, Messer J, Neu M, Olszewski A, Ronzoni R, Rowedder J, Rüdiger M, Skinner S, Smith KJ, Trottet L, Uings I, Zhu Z, Irving JA, Lomas DA. Liddle J, et al. Among authors: uings i. Bioorg Med Chem Lett. 2021 Jun 1;41:127973. doi: 10.1016/j.bmcl.2021.127973. Epub 2021 Mar 19. Bioorg Med Chem Lett. 2021. PMID: 33753261
Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin.
Lomas DA, Irving JA, Arico-Muendel C, Belyanskaya S, Brewster A, Brown M, Chung CW, Dave H, Denis A, Dodic N, Dossang A, Eddershaw P, Klimaszewska D, Haq I, Holmes DS, Hutchinson JP, Jagger AM, Jakhria T, Jigorel E, Liddle J, Lind K, Marciniak SJ, Messer J, Neu M, Olszewski A, Ordonez A, Ronzoni R, Rowedder J, Rüdiger M, Skinner S, Smith KJ, Terry R, Trottet L, Uings I, Wilson S, Zhu Z, Pearce AC. Lomas DA, et al. Among authors: uings i. EMBO Mol Med. 2021 Mar 5;13(3):e13167. doi: 10.15252/emmm.202013167. Epub 2021 Jan 29. EMBO Mol Med. 2021. PMID: 33512066 Free PMC article.
Assessment of the safety, pharmacokinetics and pharmacodynamics of GSK3335065, an inhibitor of kynurenine monooxygenase, in a randomised placebo-controlled first-in-human study in healthy volunteers.
Fernando D, Dimelow R, Gorey C, Zhu X, Muya C, Parker C, Wright W, Soleman S, Walsh S, Crause M, Vlasakakis G, Guiney W, Robertson N, Bergeal M, Cui Y, Krug AW, Uings I. Fernando D, et al. Among authors: uings i. Br J Clin Pharmacol. 2022 Feb;88(2):865-870. doi: 10.1111/bcp.15010. Epub 2021 Aug 22. Br J Clin Pharmacol. 2022. PMID: 34327739 Free article. Clinical Trial.
52 results