Acute respiratory failure due to tracheobronchial involvement in Crohn's disease

Eur Respir J. 1996 Oct;9(10):2176-8. doi: 10.1183/09031936.96.09102176.

Abstract

We present a case of tracheobronchial involvement in Crohn's disease, associated with respiratory failure leading to mechanical ventilation. Bronchoscopy revealed small, diffuse, whitish granulations and erythematous mucosa. Histopathology disclosed ulcerative bronchitis and noncaseating tuberculoid granuloma. The patient improved under a 6 week oral corticosteroid treatment followed by inhaled corticotherapy, without relapse of pulmonary symptoms.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Bronchial Diseases / complications*
  • Bronchial Diseases / drug therapy
  • Bronchial Diseases / pathology
  • Bronchoscopy
  • Crohn Disease / complications*
  • Crohn Disease / drug therapy
  • Crohn Disease / pathology
  • Glucocorticoids / therapeutic use
  • Granuloma / pathology
  • Humans
  • Male
  • Methylprednisolone / therapeutic use
  • Respiration, Artificial
  • Respiratory Insufficiency / etiology*
  • Respiratory Insufficiency / therapy
  • Tracheal Diseases / complications*
  • Tracheal Diseases / drug therapy
  • Tracheal Diseases / pathology
  • Ulcer / pathology

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Methylprednisolone