Ohkubo R[au] - Search Results

Year	Number of Results
1995	2
1996	2
1999	2
2001	1
2002	1
2003	2
2004	2
2006	1
2008	3
2010	1
2012	1
2013	2
2014	3
2015	3
2016	3
2017	1
2018	2
2019	3
2020	3
2022	1
2023	1
2024	1

1

The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging.

Wang CL, Ohkubo R, Mu WC, Chen W, Fan JL, Song Z, Maruichi A, Sudmant PH, Pisco AO, Dubal DB, Ji N, Chen D. Wang CL, et al. Among authors: ohkubo r. Cell Metab. 2023 Jun 6;35(6):996-1008.e7. doi: 10.1016/j.cmet.2023.04.012. Epub 2023 May 4. Cell Metab. 2023. PMID: 37146607

2

An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance.

He M, Chiang HH, Luo H, Zheng Z, Qiao Q, Wang L, Tan M, Ohkubo R, Mu WC, Zhao S, Wu H, Chen D. He M, et al. Among authors: ohkubo r. Cell Metab. 2020 Mar 3;31(3):580-591.e5. doi: 10.1016/j.cmet.2020.01.009. Epub 2020 Feb 6. Cell Metab. 2020. PMID: 32032542 Free PMC article.

3

The mitochondrial metabolic checkpoint in stem cell aging and rejuvenation.

Mu WC, Ohkubo R, Widjaja A, Chen D. Mu WC, et al. Among authors: ohkubo r. Mech Ageing Dev. 2020 Jun;188:111254. doi: 10.1016/j.mad.2020.111254. Epub 2020 Apr 25. Mech Ageing Dev. 2020. PMID: 32343979 Free PMC article. Review.

4

The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease.

Ohkubo R, Mu WC, Wang CL, Song Z, Barthez M, Wang Y, Mitchener N, Abdullayev R, Lee YR, Ma Y, Curtin M, Srinivasan S, Zhang X, Yang F, Sudmant PH, Pisco AO, Neff N, Haynes CM, Chen D. Ohkubo R, et al. Cell Rep. 2022 Dec 13;41(11):111803. doi: 10.1016/j.celrep.2022.111803. Cell Rep. 2022. PMID: 36516757 Free PMC article.

5

Aging: rewiring the circadian clock.

Ohkubo R, Chen D. Ohkubo R, et al. Nat Struct Mol Biol. 2017 Sep 7;24(9):687-688. doi: 10.1038/nsmb.3461. Nat Struct Mol Biol. 2017. PMID: 28880862 Free PMC article.

6

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.

McEachin ZT, Gendron TF, Raj N, García-Murias M, Banerjee A, Purcell RH, Ward PJ, Todd TW, Merritt-Garza ME, Jansen-West K, Hales CM, García-Sobrino T, Quintáns B, Holler CJ, Taylor G, San Millán B, Teijeira S, Yamashita T, Ohkubo R, Boulis NM, Xu C, Wen Z, Streichenberger N; Neuro–CEB Neuropathology Network; Fogel BL, Kukar T, Abe K, Dickson DW, Arias M, Glass JD, Jiang J, Tansey MG, Sobrido MJ, Petrucelli L, Rossoll W, Bassell GJ. McEachin ZT, et al. Among authors: ohkubo r. Neuron. 2020 Jul 22;107(2):292-305.e6. doi: 10.1016/j.neuron.2020.04.011. Epub 2020 May 5. Neuron. 2020. PMID: 32375063 Free PMC article.

7

Mutations in MME cause an autosomal-recessive Charcot-Marie-Tooth disease type 2.

Higuchi Y, Hashiguchi A, Yuan J, Yoshimura A, Mitsui J, Ishiura H, Tanaka M, Ishihara S, Tanabe H, Nozuma S, Okamoto Y, Matsuura E, Ohkubo R, Inamizu S, Shiraishi W, Yamasaki R, Ohyagi Y, Kira J, Oya Y, Yabe H, Nishikawa N, Tobisawa S, Matsuda N, Masuda M, Kugimoto C, Fukushima K, Yano S, Yoshimura J, Doi K, Nakagawa M, Morishita S, Tsuji S, Takashima H. Higuchi Y, et al. Among authors: ohkubo r. Ann Neurol. 2016 Apr;79(4):659-72. doi: 10.1002/ana.24612. Epub 2016 Mar 17. Ann Neurol. 2016. PMID: 26991897 Free PMC article.

8

Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging.

Luo H, Mu WC, Karki R, Chiang HH, Mohrin M, Shin JJ, Ohkubo R, Ito K, Kanneganti TD, Chen D. Luo H, et al. Among authors: ohkubo r. Cell Rep. 2019 Jan 22;26(4):945-954.e4. doi: 10.1016/j.celrep.2018.12.101. Cell Rep. 2019. PMID: 30673616 Free PMC article.

9

Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity.

Suzuki T, Ozasa H, Itoh Y, Zhan P, Sawada H, Mino K, Walport L, Ohkubo R, Kawamura A, Yonezawa M, Tsukada Y, Tumber A, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Schofield CJ, Miyata N. Suzuki T, et al. Among authors: ohkubo r. J Med Chem. 2013 Sep 26;56(18):7222-31. doi: 10.1021/jm400624b. Epub 2013 Sep 5. J Med Chem. 2013. PMID: 23964788 Free PMC article.

10

Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice.

Hagiya Y, Kamata S, Mitsuoka S, Okada N, Yoshida S, Yamamoto J, Ohkubo R, Abiko Y, Yamada H, Akahoshi N, Kasahara T, Kumagai Y, Ishii I. Hagiya Y, et al. Among authors: ohkubo r. Toxicol Appl Pharmacol. 2015 Jan 15;282(2):195-206. doi: 10.1016/j.taap.2014.11.015. Epub 2014 Dec 10. Toxicol Appl Pharmacol. 2015. PMID: 25499718

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