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COVID-19 mRNA vaccines: Platforms and current developments.
Szabó GT, Mahiny AJ, Vlatkovic I. Szabó GT, et al. Among authors: mahiny aj. Mol Ther. 2022 May 4;30(5):1850-1868. doi: 10.1016/j.ymthe.2022.02.016. Epub 2022 Feb 19. Mol Ther. 2022. PMID: 35189345 Free PMC article. Review.
Ribozyme Assays to Quantify the Capping Efficiency of In Vitro-Transcribed mRNA.
Vlatkovic I, Ludwig J, Boros G, Szabó GT, Reichert J, Buff M, Baiersdörfer M, Reinholz J, Mahiny AJ, Şahin U, Karikó K. Vlatkovic I, et al. Among authors: mahiny aj. Pharmaceutics. 2022 Jan 29;14(2):328. doi: 10.3390/pharmaceutics14020328. Pharmaceutics. 2022. PMID: 35214060 Free PMC article.
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans.
Sahin U, Muik A, Vogler I, Derhovanessian E, Kranz LM, Vormehr M, Quandt J, Bidmon N, Ulges A, Baum A, Pascal KE, Maurus D, Brachtendorf S, Lörks V, Sikorski J, Koch P, Hilker R, Becker D, Eller AK, Grützner J, Tonigold M, Boesler C, Rosenbaum C, Heesen L, Kühnle MC, Poran A, Dong JZ, Luxemburger U, Kemmer-Brück A, Langer D, Bexon M, Bolte S, Palanche T, Schultz A, Baumann S, Mahiny AJ, Boros G, Reinholz J, Szabó GT, Karikó K, Shi PY, Fontes-Garfias C, Perez JL, Cutler M, Cooper D, Kyratsous CA, Dormitzer PR, Jansen KU, Türeci Ö. Sahin U, et al. Among authors: mahiny aj. Nature. 2021 Jul;595(7868):572-577. doi: 10.1038/s41586-021-03653-6. Epub 2021 May 27. Nature. 2021. PMID: 34044428 Clinical Trial.
ASL mRNA-LNP Therapeutic for the Treatment of Argininosuccinic Aciduria Enables Survival Benefit in a Mouse Model.
Daly O, Mahiny AJ, Majeski S, McClintock K, Reichert J, Boros G, Szabó GT, Reinholz J, Schreiner P, Reid S, Lam K, Lepper M, Adler M, Meffen T, Heyes J, Karikó K, Lutwyche P, Vlatkovic I. Daly O, et al. Among authors: mahiny aj. Biomedicines. 2023 Jun 16;11(6):1735. doi: 10.3390/biomedicines11061735. Biomedicines. 2023. PMID: 37371829 Free PMC article.
In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency.
Mahiny AJ, Dewerth A, Mays LE, Alkhaled M, Mothes B, Malaeksefat E, Loretz B, Rottenberger J, Brosch DM, Reautschnig P, Surapolchai P, Zeyer F, Schams A, Carevic M, Bakele M, Griese M, Schwab M, Nürnberg B, Beer-Hammer S, Handgretinger R, Hartl D, Lehr CM, Kormann MS. Mahiny AJ, et al. Nat Biotechnol. 2015 Jun;33(6):584-6. doi: 10.1038/nbt.3241. Epub 2015 May 18. Nat Biotechnol. 2015. PMID: 25985262 No abstract available.
Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.
Raifer H, Mahiny AJ, Bollig N, Petermann F, Hellhund A, Kellner K, Guralnik A, Reinhard K, Bothur E, Huber M, Bauer S, Löhning M, Kiss EA, Ganal SC, Diefenbach A, Korn T, Lohoff M. Raifer H, et al. Among authors: mahiny aj. Eur J Immunol. 2012 Dec;42(12):3189-201. doi: 10.1002/eji.201142155. Epub 2012 Oct 17. Eur J Immunol. 2012. PMID: 22961652 Free article.