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Page 1
Blocking TRPA1 in Respiratory Disorders: Does It Hold a Promise?
Mukhopadhyay I, Kulkarni A, Khairatkar-Joshi N. Mukhopadhyay I, et al. Among authors: khairatkar joshi n. Pharmaceuticals (Basel). 2016 Nov 5;9(4):70. doi: 10.3390/ph9040070. Pharmaceuticals (Basel). 2016. PMID: 27827953 Free PMC article. Review.
Synthesis and pharmacological evaluation of novel N-aryl-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]-1'-carboxamides as TRPM8 antagonists.
Chaudhari SS, Kadam AB, Khairatkar-Joshi N, Mukhopadhyay I, Karnik PV, Raghuram A, Rao SS, Vaiyapuri TS, Wale DP, Bhosale VM, Gudi GS, Sangana RR, Thomas A. Chaudhari SS, et al. Among authors: khairatkar joshi n. Bioorg Med Chem. 2013 Nov 1;21(21):6542-53. doi: 10.1016/j.bmc.2013.08.031. Epub 2013 Aug 29. Bioorg Med Chem. 2013. PMID: 24055075
Discovery of benzo[d]imidazo[5,1-b]thiazole as a new class of phosphodiesterase 10A inhibitors.
Banerjee A, Narayana L, Raje FA, Pisal DV, Kadam PA, Gullapalli S, Kumar H, More SV, Bajpai M, Sangana RR, Jadhav S, Gudi GS, Khairatkar-Joshi N, Merugu RR, Voleti SR, Gharat LA. Banerjee A, et al. Among authors: khairatkar joshi n. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6747-54. doi: 10.1016/j.bmcl.2013.10.027. Epub 2013 Oct 26. Bioorg Med Chem Lett. 2013. PMID: 24231362
Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2',3':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor.
Muthukaman N, Deshmukh S, Sarode N, Tondlekar S, Tambe M, Pisal D, Shaikh M, Kattige VG, Honnegowda S, Karande V, Kulkarni A, Jadhav SB, Mahat MYA, Gudi GS, Khairatkar-Joshi N, Gharat LA. Muthukaman N, et al. Among authors: khairatkar joshi n. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5977-5984. doi: 10.1016/j.bmcl.2016.10.079. Epub 2016 Nov 1. Bioorg Med Chem Lett. 2016. PMID: 27865703
Discovery of 5-(2-chloro-4'-(1H-imidazol-1-yl)-[1,1'-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD.
Muthukaman N, Deshmukh S, Tondlekar S, Tambe M, Pisal D, Sarode N, Mhatre S, Chakraborti S, Shah D, Bhosale VM, Kulkarni A, Mahat MYA, Jadhav SB, Gudi GS, Khairatkar-Joshi N, Gharat LA. Muthukaman N, et al. Among authors: khairatkar joshi n. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3766-3773. doi: 10.1016/j.bmcl.2018.10.012. Epub 2018 Oct 10. Bioorg Med Chem Lett. 2018. PMID: 30340896
Design, Synthesis, and Pharmacological Evaluation of 5,6-Disubstituted Pyridin-2(1H)-one Derivatives as Phosphodiesterase 10A (PDE10A) Antagonists.
Lingam VS, Dahale DH, Rathi VE, Shingote YB, Thakur RR, Mindhe AS, Kummari S, Khairatkar-Joshi N, Bajpai M, Shah DM, Sapalya RS, Gullapalli S, Gupta PK, Gudi GS, Jadhav SB, Pattem R, Thomas A. Lingam VS, et al. Among authors: khairatkar joshi n. J Med Chem. 2015 Oct 22;58(20):8292-308. doi: 10.1021/acs.jmedchem.5b01240. Epub 2015 Oct 7. J Med Chem. 2015. PMID: 26421921
Alleviating CYP and hERG liabilities by structure optimization of dihydrofuran-fused tricyclic benzo[d]imidazole series - Potent, selective and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-2.
Muthukaman N, Deshmukh S, Tambe M, Pisal D, Tondlekar S, Shaikh M, Sarode N, Kattige VG, Sawant P, Pisat M, Karande V, Honnegowda S, Kulkarni A, Behera D, Jadhav SB, Sangana RR, Gudi GS, Khairatkar-Joshi N, Gharat LA. Muthukaman N, et al. Among authors: khairatkar joshi n. Bioorg Med Chem Lett. 2018 Apr 15;28(7):1211-1218. doi: 10.1016/j.bmcl.2018.02.048. Epub 2018 Feb 28. Bioorg Med Chem Lett. 2018. PMID: 29519738
16 results