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Page 1
Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis.
Bierwagen J, Wiegand M, Laakmann K, Danov O, Limburg H, Herbel SM, Heimerl T, Dorna J, Jonigk D, Preußer C, Bertrams W, Braun A, Sewald K, Schulte LN, Bauer S, Pogge von Strandmann E, Böttcher-Friebertshäuser E, Schmeck B, Jung AL. Bierwagen J, et al. Among authors: danov o. Cell Commun Signal. 2023 Mar 28;21(1):65. doi: 10.1186/s12964-023-01086-4. Cell Commun Signal. 2023. PMID: 36978183 Free PMC article.
Cyclosporin A Reveals Potent Antiviral Effects in Preclinical Models of SARS-CoV-2 Infection.
Sauerhering L, Kuznetsova I, Kupke A, Meier L, Halwe S, Rohde C, Schmidt J, Morty RE, Danov O, Braun A, Vadász I, Becker S, Herold S. Sauerhering L, et al. Among authors: danov o. Am J Respir Crit Care Med. 2022 Apr 15;205(8):964-968. doi: 10.1164/rccm.202108-1830LE. Am J Respir Crit Care Med. 2022. PMID: 35167409 Free PMC article. No abstract available.
COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy.
Weckmann M, Bahmer T, Sand JM, Rank Rønnow S, Pech M, Vermeulen C, Faiz A, Leeming DJ, Karsdal MA, Lunding L, Oliver BGG, Wegmann M, Ulrich-Merzenich G, Juergens UR, Duhn J, Laumonnier Y, Danov O, Sewald K, Zissler U, Jonker M, König I, Hansen G, von Mutius E, Fuchs O, Dittrich AM, Schaub B, Happle C, Rabe KF, van de Berge M, Burgess JK, Kopp MV; ALLIANCE Study Group as part of the German Centre for Lung Research (DZL). Weckmann M, et al. Among authors: danov o. Eur Respir J. 2021 Dec 9;58(6):2003969. doi: 10.1183/13993003.03969-2020. Print 2021 Dec. Eur Respir J. 2021. PMID: 34326188 Free article.
Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs.
Danov O, Jiménez Delgado SM, Obernolte H, Seehase S, Dehmel S, Braubach P, Fieguth HG, Matschiner G, Fitzgerald M, Jonigk D, Knauf S, Pfennig O, Warnecke G, Wichmann J, Braun A, Sewald K. Danov O, et al. PLoS One. 2018 Nov 30;13(11):e0207767. doi: 10.1371/journal.pone.0207767. eCollection 2018. PLoS One. 2018. PMID: 30500834 Free PMC article.
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
Hoffmann M, Hofmann-Winkler H, Smith JC, Krüger N, Arora P, Sørensen LK, Søgaard OS, Hasselstrøm JB, Winkler M, Hempel T, Raich L, Olsson S, Danov O, Jonigk D, Yamazoe T, Yamatsuta K, Mizuno H, Ludwig S, Noé F, Kjolby M, Braun A, Sheltzer JM, Pöhlmann S. Hoffmann M, et al. Among authors: danov o. EBioMedicine. 2021 Mar;65:103255. doi: 10.1016/j.ebiom.2021.103255. Epub 2021 Mar 4. EBioMedicine. 2021. PMID: 33676899 Free PMC article.
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