Abstract
Introduction: Primary graft dysfunction (PGD) is a multifactorial injury to the transplanted lung that develops within the first 72 hours after transplantation (LTx). The aim of this study was to evaluate the incidence of PGD grade 3 (defined by a P/F ratio < 200) and its relationship with medium and long term functional results.
Methods: A retrospective study was conducted including all lung tranplant recipients from January 2009 to June 2014. The incidence of PGD3 was evaluated both in those who underwent ECMO as bridge to LTx and the rest of the population. Two groups of patients were identified: those who developed PGD3 and those who did not. All data were statistically analized with SPSS version 22 for Macintosh. Descriptive statistics were reported with continuous data expressed as mean ± SD and categorical data expressed as counts. Comparisons between groups were performed using Student T test and Chi Square test.
Results: 76 patients were considered. Results are depicted in table 1 and figure 1.
Conclusions: ECMO seemed to be a possible risk factor for PGD3. Although no significant difference was found between the incidence of CLAD in the two groups, BestFEV1 proved to be significantly higher in those individuals who did not develop PGD.
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