Abstract
I: Diabetes mellitus (DM) is considered an immunosuppression state with higher risk of infection. The goal of this study was to evaluate if diabetic patients had higher proportion of microbiological isolates in community-acquired pneumonia (CAP) admitted patients.
M: Retrospective cohort study. All patients admitted to our hospital between 01/2010 and 11/2011 with CAP diagnosis were evaluated: files were reviewed and patients without clear clinical/radiological signs of pneumonia were excluded. General demographics and DM status were recorded as well as all biological products collected at admission and microbiological isolates. Descriptive statistics, Chi-square and Mann-Whitney tests were performed; p significance < 0,05 (Software: IBM SPSS version 21).
R: 171 patients were included; males were 69.5% on DMg (DM group) vs 58.7% on nDM (non-DM group) (p=0.168); mean age (years) was 76.8 (±12.7) on nDM vs 68.4 (±16.7) on DMg (p=0.001). Mean admission time was 11.8 (±9.2) days on nDM vs 12.9 (±8.3) on DMg (p=0.21). From nDM 13.8% collected sputum, 66.1% collected blood for culture and 36.7% collected urine; from DMg 13.6% collected sputum, 62.7% collected blood for culture and 37.3% collected urine. Only 1.8% of nDM had isolates on sputum and blood (vs 0% on DMg) and 3.7% on urine (vs 10.2% on DMg), p=0.52, 0.55 and 0.15 respectively. Haemophilus influenzae and Klebsiella pneumoniae were the agents isolated in sputum, staphylococcal aureus on blood and E.coli was the commonest urine bacteria.
C: In spite of being considered an immunosuppression state, diabetics had no higher levels of identification of bacteria on sputum, urine or blood.
- Copyright ©ERS 2015