Abstract
BACKGROUND
The fraction of exhaled nitric oxde (FeNO) is a useful marker of eosinophilic airway inflammation in asthmatics. The FeNO measurement with two offline methods and NO breath may be more affordable, small number of studies have examined the differences in FeNO values measured with various methods in adult Japanese.
METHODS
The study population comprised 44 patient (male/female: 14/30; mean age: 51.8±15.0 years; bronchial asthma/other respiratory disorders: 27/17) at our hospital. FeNO value were measured by two offline methods (Sievers and CEIS), NO breath.
RESULTS
FeNONO breath value were significantly correlated with those FeNOSievers (r=0.87) and FeNOCEIS (r=0.89). FeNONO breath values were nearly equal FeNOSievers (FeNONO breath=1.1 x FeNOSievers), however these values were low compared with FeNOCEIS (FeNONO breath=0.75 x FeNOCEIS)(p=0.02).
CONCLUSION
Difference exist in the values of FeNO measured by various methods: conversion equations are needed to compare the FeNO values among these three methods.
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