Abstract
Background: COPD is a multisystem disorder with significant extrapulmonary manifestations.
Aims: To assess cognitive functions in stable COPD patients using PGI Memory Scale Questionnaire [PGIMSQ] and to seek for any correlation with patients' characteristics and BODE index variables.
Methods: We included 200 stable COPD patients and 50 healthy volunteers [HV]. Their baseline characteristics and BODE index variables were assessed. PGIMSQ was used to assess cognitive functions under 10 subsets (shown in Table 1).
Results: The age of subjects in COPD Group was 61.37 ± 7.4 year, and of those in HV group was 59.76 ± 7.21 year. 105 COPD patients (52.5%) were having PGIMSQ scores beyond ± 3 SD of HV scores. PGIMSQ scores are shown in Table 1.
Age, duration of illness, MMRC dyspnea and BODE index scores had inverse correlations with PGIMSQ scores. FEV1 and distance walked in six minute had positive correlations with PGIMSQ scores.
Conclusions: We observed a global decline of cognitive functions in COPD group and observed their significant correlations with age, duration of illness and BODE index variables.
- © 2012 ERS