Fig. 3. –

A representative cystic fibrosis (CF) bone biopsy alongside a normal control biopsy. (a) CF subject: Toluidine blue stained section of iliac crest bone biopsy showing decreased cancellous bone connectivity and decreased cancellous bone area. b) CF subject: Higher power magnification of boxed area demonstrating thin wall width as compared with control. c) Normal subject: Toluidine blue stained section of iliac crest bone biopsy from a normal patient demonstrating good connectivity of cancellous bone. d) Normal subject: Higher power magnification of boxed area showing normal wall width of two complete packets. White arrows: wall width of bone packets; black arrows: crenated surface of a shallow resorption cavity. Reprinted from Elkin et al. [20] with permission.