Summary:
Changes in operating lung volumes as ventilation increases with exercise in a) chronic obstructive pulmonary disease (COPD); and b) age-matched healthy subjects. End-expiratory lung volume (EELV) increases above the relaxation volume of the respiratory system (Vr) in COPD, as reflected by a decrease in inspiratory capacity (IC), whereas EELV in health either remains unchanged or decreases. Restrictive constraints on tidal volume (VT) expansion (╦) during exercise are significantly greater in the COPD group from both below (increased EELV) and above (reduced inspiratory reserve volume (IRV) as end-inspiratory lung volume (EILV) approaches total lung capacity (TLC)). ERV: expiratory reserve volume; RV: residual volume; VC: vital capacity; % pred: % predicted. Adapted from [29] with permission.
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Figure
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Normal
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F32
Highwire: Type:
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ersbk
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Highwire: Variants:
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Highwire: State:
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Contributors:
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