Summary:
a–i) Graphic representations of metabolic (a, c), cardiovascular (d, g), ventilatory (b, e, f, h) and gas-exchange (i) responses to incremental CPET in a 23-year-old woman (Medical Research Council dyspnoea scale score of 3) with combined O2 delivery/utilisation and gas-exchange impairment due to PAH associated with congenital heart disease (secundum atrial septal defect). See text for further details. For explanations of graphs, see figure 1. Dashed black parallel lines in a), d) and e) indicate the expected values of the dependent variable (y). Max pred: maximum predicted; S: slope; unload: unloaded exercise; rec: recovery; I: intercept; VC: vital capacity; RR: respiratory rate. Reproduced and modified from [36] with permission.
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F29
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